With intelligent tools and services for your cell line development needs, Sartorius has solutions for every stage of the journey to commercialization. Explore the CLD solutions: https://www.sartorius.com/en/applications/biopharmaceutical-manufacturing/cell-line-development?utm_source=youtube&utm_medium=socialorganic&utm_campaign=cld-bps-lps-initiative&utm_term=cld&mrksrc=social&utm_content=youtube-video Bringing a biologic to market depends on smart cell line development strategies. You need to balance the control and speed of an in-house solution with the convenience and flexibility of outsourcing. Sartorius offers a suite of innovative products and services that can be tailored to your operation.  Whether you need instruments, consulting, or development and testing services, partnering with Sartorius can accelerate your cell line development and ensure a smooth transition to commercial manufacturing.   Watch this video to learn more about cell line development solutions from Sartorius.  Follow us on LinkedIn: https://www.linkedin.com/company/sartorius Do not forget to subscribe to have better access to our videos! #celllinedevelopment #drugdiscovery #mAbs

Even the most innovative R&D organizations still face significant data challenges in cell line development (CLD). Modern CLD is becoming increasingly sophisticated and has served as a foundation for recent advancements in biologics, vaccine development, and even cultured meats. In this webinar, get best practices for screening hits more efficiently, managing real-time inventory, plus advice on collecting, analyzing, and visualizing CLD efficiently.

Presented At: Molecular Diagnostics Virtual Event 2018 Presented By: Barbara McIntosh Vice President, Business Development, Scienion Alba Simon Marketing Manager, Scienion Guilhem Tourniaire Scientific and General Director, Cellenion Speaker Bio: Barbara McIntosh - Barbara McIntosh, Vice President for Business Development at SCIENION US since 2016. For over 20 years, Barbara has been working in the diagnostic and life science marketplace on specific point of care applications like continuous glucose monitoring (CGM), lateral flow, multiplex arrays, and other microfluidic devices. She has been both an invited speaker at global conferences as well as a published author. She holds a BS degree in Biology and a MS in Management. bmcintosh@scienion.com Alba Simon - Originally from Spain, Alba holds a Master's Degree in Chemical Engineering from Strasbourg University and has been employed at SCIENION for two years now. She has been working closely with key accounts on the Mediterranean area, including diagnostic companies, medical centres and hospitals and research institutes in Spain, France, Italy and Portugal to introduce SCIENION dispensing technology and new cellenONE technology. Since recently, she is heading the Marketing Department. a.simon@scienion.com Guilhem Tourniaire - Guilhem studied Chemistry at the IUT of Montpellier, after an industrial placement at Unilever in Liverpool, he decided to further his study in the United Kingdom. There he undertook a Masters in Applied Chemistry from Kingston University and then received a PhD in high throughput Chemical Biology under the supervision of Professor Mark Bradley at the University of Edinburgh. After graduating he worked for several start-up companies. At Smart Holograms, he worked on the development of biosensors for glucose monitoring. At Altrika, he was project manager and developed biomaterials for stem cell culture and bacterial enrichment. In 2013, he decided to return to France and started working as sales manager and business developer for a German company called SCIENION AG. As part of this position, he established a business plan to investigate novel markets and applications related to precision cell dispensing. This latest assignment led to the creation of Cellenion in 2016, and his appointment as Scientific and Managing director. Cellenion is based in Lyon and specializes in the fields of bioprinting and single-cell isolation. Webinar: How Can CellenONE Technology Help You Automate Cell Line Development? Webinar Abstract: Historically single cell isolation techniques suffered from poor efficiency, low recovery and difficult automation, among other limitations. This presentation will highlight cellenONE, a piezo-acoustic and visual feedback technology to isolate and dispense single cells. Case studies have shown outstanding accuracy, high viability; both crucial parameters for cell line development. Earn PACE/CME Credits: 1. Make sure you’re a registered member of LabRoots (https://www.labroots.com/virtual-event/molecular-diagnostics-2018) 2. Watch the webinar on YouTube above or on the LabRoots Website (https://www.labroots.com/virtual-event/molecular-diagnostics-2018) 3. Click Here to get your PACE (Expiration date – April 11, 2020 12:00 AM)– http://www.labroots.com/credit/pace-credits/2849/third-party LabRoots on Social: Facebook: https://www.facebook.com/LabRootsInc Twitter: https://twitter.com/LabRoots LinkedIn: https://www.linkedin.com/company/labr... Instagram: https://www.instagram.com/labrootsinc Pinterest: https://www.pinterest.com/labroots/ SnapChat: labroots_inc

Interested in rapid and efficient stable cell pool/cell line development for large-scale production of your recombinant antibodies and proteins? In this session, we will review some basic information about generating a stable cell pool/cell line using the Glutamine Synthetase (GS)-based system. We will also compare the usability of GS system alongside the Dihydrofolate Reductase (DHFR) system for different applications. Topics such as how to efficiently screen stable pool/stable clones for increased expression, how to monitor the consistency, reliability, robustness and potency of products during scale-up will also be discussed.

Engineered cell lines stably overexpressing GPCRs are useful models for detection of GPCR signaling. Creative Biogene owns a team of experienced GPCR biologists working in the area of GPCR biology and drug discovery. We have generated a wide variety of GPCR stable cells with more under development.

Presented by: Bo Zhai, Cell & Developability Science, Janssen Research & Development As biopharmaceuticals have been at the center stage of the pipeline of almost every pharmaceutical company, high-yield, stably expressing cell lines are of critical importance for economically viable biopharmaceutical production processes. Tracking CLD process have been proven challenging given the number of clones generated, as well as tests performed to identify producer cell lines suitable for industrial, large-scale manufacturing processes. Using LabKey Biologics, we mapped the whole cell line development process with proper lineage tracking. Associate the molecule entity as well as analytical testing information with samples at different CLD stages effectively reduced clone selection timeline.

Discover more from the In Focus here: https://bit.ly/3XgsI0C Including a podcast exploring cell-line development: https://bit.ly/3GURIVG And an infographic with common challenges in cell-line development and how to overcome them: https://bit.ly/3XmBCtk Introducing cell-line development (CLD), this video covers the five key steps involved in CLD and where challenges arise. In order to manufacture a biopharmaceutical product, such as monoclonal antibodies and viral vectors, researchers need to determine the cell line best suited for producing it. Once selected, they need to ensure that it withstands scale-up, maintaining the quality of the biologic produced at a manufacturing scale.