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  •  DATA EXHIBITS

    125


TABLE OF CONTENTS


   Pages :    | $

   Study Reliability and Reporting Limitations.....I-1  
   Disclaimers.....I-2
Data Interpretation & Reporting Level.....I-2
  
   Product Definitions and Scope of Study.....I-3  
   Introduction.....II-1
Demand and Sales Remain Cyclic and Seasonal.....II-1
Women & Kids - Primary Consumers of Cold and Cough Remedies.....II-1
1$100
   FDA Discourages Use of Hydrocodone in Cough Medicines.....II-2
List of Antitussive Products (Containing Hydrocodone) Approved by the USFDA as of
  2008.....II-2
OTC Medications for Children May Pose Health Risks.....II-2
1$100
   Regulatory Agencies Revise OTC Drugs List.....II-3
CHPA Voluntarily Revises OTC Labels.....II-3
FDA Raises Red Flag for Acetaminophen.....II-3
OTC Drugs Move to Supermarkets.....II-3
Convenience Drives OTC Cold Cough Remedies Sales.....II-3
Delayed Winters Reduce Quarterly Revenues.....II-3
1$100
   Key Growth Drivers.....II-4
Economic Slowdown.....II-4
Swine Flu.....II-4
The Need to Reduce Sick Leaves.....II-4
Growing Awareness about Rest Period.....II-4
OTC Industry – A Brief.....II-4
1$100
   Table 1: World OTC Products Market (2008): Percentage Breakdown of Retail Value Sales by Category - Analgesics, Cold/Cough, Digestives, Vitamins, Minerals, and Supplements, Skincare, and Others (includes corresponding Graph/Chart).....II-5

Table 2: World Market for Nasal Congestion Products (2008): Leading Players by Number of Marketed Products (includes corresponding Graph/Chart).....II-5
1$350
   Common cold.....II-6
Background and Etymology.....II-6
Common Cold Viruses.....II-6
1$100
   Major Causes for Common Cold.....II-7
Symptoms of Common Cold.....II-7
1$100
   Diagnosis.....II-8
Incubation Period and Disease Progression.....II-8
Common Cold- Affects on Other Body Parts.....II-8
1$100
   Prevention of Common Cold.....II-9
Common Cold Remedies.....II-9
Effective Medications.....II-9
1$100
   Zinc Lozenges.....II-10
Astragalus.....II-10
Pleconaril.....II-10
Limitations of Medications.....II-10
Antibiotics.....II-10
Antihistamines.....II-10
1$100
   Over-the-Counter Medications.....II-11
Antihistamines.....II-11
Decongestants.....II-11
1$100
   Pain Relievers.....II-12
Antitussives.....II-12
Expectorants.....II-12
Precautions Related with Common Cold Medicine.....II-12
1$100
   Other Information.....II-13
Effective Home Remedies.....II-13
3$175
   Cough.....II-161$100
   Causes of Cough.....II-171$100
   Symptoms and Diagnosis.....II-18
Physical Examination.....II-18
Testing.....II-18
1$100
   Complications.....II-19
Cough Remedies.....II-19
Decongestants.....II-19
Expectorants and Suppressants.....II-19
1$100
   Cough Suppressants.....II-20
Cough Expectorants.....II-20
Herbal Expectorants.....II-20
1$100
   Corticosteroids.....II-21
Bronchodilators.....II-21
Nasal Corticosteroids.....II-21
Antihistamines.....II-21
Antitussive Agents.....II-21
1$100
   Alternative Treatments and Supplementary Diets.....II-222$125
   Other Alternative Treatments Based on Types of Cough.....II-24
Cough Caused Due to the Impairment of Internal Organs.....II-24
Attack of Sputum-Dampness on the Lungs.....II-24
1$100
   Heat-Sputum in the lungs.....II-25
Attack of Liver-Fire on the Lungs.....II-25
Consumption of the lung-yin.....II-25
Cough caused due to the Invasion of Exogenous Pathogenic Factors.....II-25
Wind Cold.....II-25
Wind-Heat.....II-25
Heat-Dryness.....II-25
1$100
   Nagging Cough.....II-26
Symptoms.....II-26
Prevention/Solution.....II-26
Sore Throat.....II-26
1$100
   Types of Sore Throats Based on Causes.....II-271$100
   Viral Sore Throat.....II-28
Bacterial Sore Throat.....II-28
1$100
   Noninfectious Sore Throat.....II-29
Sore Throat Due to Drug Interactions.....II-29
Other Causes.....II-29
Symptoms and Diagnosis.....II-29
1$100
   Complications.....II-30
Medical Remedies.....II-30
1$100
   Mitamins Advanced Formula (MAF).....II-31
Carbimazole Drugs.....II-31
Antibiotics.....II-31
1$100
   Other Drugs.....II-32
Alternative Treatments.....II-32
Homeopathy.....II-32
Home Remedies.....II-32
2$125
   Common Home Remedies to Reduce Throat Pain.....II-341$100
   Herbal Medicines.....II-35
Nutritional Therapy.....II-35
1$100
   Ayurvedic Medicines.....II-36
Aromatherapy.....II-36
1$100
   Other Sore Throat Therapies.....II-37
Common Drugs Used for Cold, Cough, and Sore Throat.....II-37
1$100
   Evolution of Cold, Cough, & Sore Throat Remedies – A Historic Review.....II-38
Cold Remedies- Drug/Treatment Option/ Product Name.....II-38
1$100
   Cough Remedies - Drug/Treatment Option/Product Name.....II-39
Sore Throat Remedies - Drug/Treatment Option/Product Name.....II-39
Cold Cough and Sore Throat Symptoms & Treatment: A Special Focus on Children.....II-39
1$100
   Etiology of Cough in Children.....II-40
Whooping Cough in Children.....II-40
1$100
   Risk Factors and Causes.....II-41
Symptoms.....II-41
Diagnosis and Treatment.....II-41
OTC Treatment Options.....II-41
1$100
   Natural Health Remedies.....II-421$100
   Prevention.....II-43
Treatment for Cough in Infants and Babies.....II-43
Whooping Cough Vaccines.....II-43
1$100
   Treatment for Cough in Teenagers & Adults.....II-44
Alternative Medicines for Whooping Cough.....II-44
1$100
   Therapeutic principles.....II-45
Syndrome Differentiation.....II-45
Classification and Treatment.....II-45
2$125
   Cadbury Launches HALLS Refresh.....II-47
McNeil Introduces ZYRTEC® Allergy Bubble Gum Syrup.....II-47
Honey, Don't Cough Introduces Children's Buckwheat Honey.....II-47
Honey Naturals to Launch ZarBee's™ Children's Cough Syrup.....II-47
Hyland's Launches Cold Relief with Zinc 4 Kids.....II-47
Mach One Corporation Develops Swine Flu Virus Solution.....II-47
1$100
   Schwabe Pharmaceuticals Unveils Zucol.....II-48
Schering-Plough Launches Afrin.....II-48
Auriga Introduces New Extendryl® Products.....II-48
Boiron Introduces Children's Coldcalm® and Children's Oscillococcinum®.....II-48
1$100
   Covidien Pharmaceutical Products Introduces TussiCaps®.....II-49
Hamdard Introduces Herbal Cough and Cold Medicines.....II-49
Insight Introduces Sucrets ICE.....II-49
1$100
   Med-Systems Launches Pediatric Nasal Spray.....II-50
Health Care Products to Launch Nasal Ease Products.....II-50
Plethico Pharmaceuticals Introduces Travisil®.....II-50
St. Paul Brands Launches Fizzy Drink Remedy.....II-50
Oasis to Unveil Oasis Nasal Spray and Wash.....II-50
Auriga Laboratories Introduces Zinx Cold Relief Products.....II-50
1$100
   Sanofi-Aventis Introduces Balsamic Decongestant Cream.....II-511$100
   First Boston Pharma Acquires NutraMax Products.....II-52
FDA Halts Zicam Cold Remedy Sales.....II-52
Genomma Lab Takes Over Medicinas y Medicamentos Nacionales.....II-52
GSK Abandons Production of Actified.....II-52
Johnson & Johnson Acquires Cougar Biotechnology.....II-52
1$100
   Laiyang Jiangbo Inks Purchase Agreement with Hongrui.....II-53
Lupin Acquires Rights for AllerNaze™ from Collegium Pharmaceutical.....II-53
Pfizer Announces Plans to Take Over Wyeth.....II-53
Alcon Receives Approval for Patanase.....II-53
1$100
   BHC Acquires Topsun (OTC) Cough and Cold Portfolio.....II-54
MiddleBrook Receives FDA Approval for MOXATAG™ Tablets.....II-54
Neuro-Hitech Acquires AMBI and MCR.....II-54
Perrigo Acquires Galpharm Healthcare.....II-54
Perrigo Acquires Distribution Rights for Levocetirizine.....II-54
1$100
   Sun Pharma Receives FDA Approval for Generic Anti-Cough Drug.....II-55
Meda AB Acquires MedPointe, Inc......II-55
Reckitt Benckiser to Acquire Adams Respiratory Therapeutics.....II-55
1$100
   Aaron Industries, Inc. (US).....II-56
AccuMed, Inc. (US).....II-56
Bayer Corporation (US).....II-56
Biozone Laboratories, Inc. (US).....II-56
1$100
   First Boston Pharma, LLC (US).....II-57
GlaxoSmithKline Pharmaceuticals, Limited (India).....II-57
G.R.Lane Health Products, Limited (UK).....II-57
Johnson & Johnson (US).....II-57
Kalbe Farma Tbk (Indonesia).....II-57
1$100
   Matrixx Initiatives, Inc. (US).....II-58
Zicam, LLC (US).....II-58
NIZHPHARM OAO (Russia).....II-58
Novartis AG (Switzerland).....II-58
Perrigo Company (US).....II-58
1$100
   Pharmstandard Group (Russia).....II-59
P. J. Noyes Company Inc (US).....II-59
Procter & Gamble (US).....II-59
1$100
   Ranbaxy Laboratories Limited (India).....II-60
Reckitt Benckiser Group plc (UK).....II-60
Schering-Plough Corporation (US).....II-60
1$100
   Taro Pharmaceuticals USA, Inc. (US).....II-61
Teva Pharmaceutical Industries Ltd. (Israel).....II-61
Thornton & Ross Ltd (UK).....II-61
Wyeth Consumer Healthcare (US).....II-61
1$100
   Table 3: World Recent Past, Current & Future Analysis for Cold, Cough and Sore Throat Remedies by Geographic Region - US, Canada, Japan, Europe, and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for the Years 2006 through 2015 (includes corresponding Graph/Chart).....II-621$350
   Table 4: World 9-Year Perspective for Cold, Cough and Sore Throat Remedies by Geographic Region - Percentage Breakdown of Dollar Sales for US, Canada, Japan, Europe, and Rest of World Markets for the Years 2006, 2009 & 2015 (includes corresponding Graph/Chart).....II-631$350
   A. Market Analysis.....III-1
Outlook.....III-1
Overview.....III-1
OTC Sales Grow Despite Ongoing Debate Over Use in Children.....III-1
Private Labels Dominate.....III-1
1$75
   OTC Products Market.....III-2
Table 5: US OTC Products Market (2008): Percentage Breakdown of Retail Value Sales by Category - Cold and Cough, Digestives, Internal Analgesics, Nutritional Products, Topical Products, and Others (includes corresponding Graph/Chart).....III-2

Table 6: US OTC Products Market (2008): Percentage Breakdown of Retail Value Sales by Leading Companies - Bayer Group, GlaxoSmithKline, Johnson & Johnson, Procter & Gamble, Wyeth, and Others (includes corresponding Graph/Chart).....III-2
1$200
   Table 7: US OTC Products Market (2008): Percentage Breakdown of Retail Value Sales by Outlet Type - Drug Stores, Food Stores, Mass Merchandisers, and Others (includes corresponding Graph/Chart).....III-3
Major Brands.....III-3
Table 8: Leading Brands in the US Nasal Sprays/ Inhalers/Drops Market (2008): Percentage Breakdown of Retail Value Sales by Brand - Afrin, Afrin No Drip, Ayr, Blairex Simply Saline, NeilMed, Primatene Mist, SinuCleanse, Vicks, Vicks Sinex, Zicam, and Others (includes corresponding Graph/Chart).....III-3
1$200
   Table 9: Leading Brands in the US Nasal Sprays/ Inhalers/Drops Market (2008): Percentage Breakdown of Retail Volume Sales by Brand - Afrin, Afrin No Drip, Ayr, Blairex Simply Saline, NeilMed, Primatene Mist, SinuCleanse, Vicks, Vicks Sinex, Zicam, and Others (includes corresponding Graph/Chart).....III-4

Table 10: Leading Brands in the US Cough/Cold - Chest Rubs Market (2008): Percentage Breakdown of Retail Value Sales by Brand - Little Colds, Mentholatum, Theraflu Vapor Patch, Vicks Baby Rub, Vicks Casero, Vicks VapoRub, Private Label, and Others (includes corresponding Graph/Chart).....III-4
1$200
   Table 11: Leading Brands in the US Cough/Cold - Chest Rubs Market (2008): Percentage Breakdown of Retail Value Sales by Brand - Little Colds, Mentholatum, Theraflu Vapor Patch, Vicks Baby Rub, Vicks Casero, Vicks VapoRub, Private Label, and Others (includes corresponding Graph/Chart).....III-5

Table 12: Leading Brands in the US Cold/Allergy/ Sinus (Tablets/Packets) Market (2008): Percentage Breakdown of Retail Value Sales by Brand - Airborne, Benadryl, Clarion D, Claritin, Mucinex, Mucinex D, Mucinex DM, Sudafed PE, Tylenol Cold, Zyrtec, Private Label, and Others (includes corresponding Graph/Chart).....III-5
1$200
   Table 13: Leading Brands in the US Cold/Allergy/ Sinus (Tablets/Packets) Market (2008): Percentage Breakdown of Retail Volume Sales by Brand - Airborne, Benadryl, Clarion D, Claritin, Mucinex, Mucinex D, Mucinex DM, Sudafed PE, Tylenol Cold, Zyrtec, Private Label, and Others (includes corresponding Graph/Chart).....III-6

Table 14: Leading Brands in the US Cold/Allergy/ Sinus (Liquid/Powder) Market (2008): Percentage Breakdown of Retail Value Sales by Brand - Benadryl, Children's Tylenol, Dimetapp, Robitussin, Robitussin CF, Theraflu, Triaminic, Tylenol, Tylenol Cold, Vicks NyQuil, Private Label, and Others (includes corresponding Graph/Chart).....III-6
1$200
   Table 15: Leading Brands in the US Cold/Allergy/ Sinus (Liquid/Powder) Market (2008): Percentage Breakdown of Retail Volume Sales by Brand - Benadryl, Children's Tylenol, Dimetapp, Robitussin, Robitussin CF, Theraflu, Triaminic, Tylenol, Tylenol Cold, Vicks NyQuil, Private Label, and Others (includes corresponding Graph/Chart).....III-71$200
   Table 16: Leading Brands in the US Cough Syrup/ Sore Throat Remedy Liquids Market (2008): Percentage Breakdown of Retail Value Sales by Brand - Airborne, Benadryl, Clarion D, Claritin, Mucinex, Mucinex D, Mucinex DM, Sudafed PE, Tylenol Cold, Zyrtec, Private Label, and Others (includes corresponding Graph/Chart).....III-81$200
   Table 17: Leading Brands in the US Cough Syrup/Sore Throat Remedy Liquids Market (2008): Percentage Breakdown of Retail Volume Sales by Brand - Chloraseptic Sore Throat Remedy, Delsym Cough Syrup, Diabetic Tussin Cough Syrup, Robitussin Cough Syrup, Private Label, and Others (includes corresponding Graph/Chart).....III-91$200
   Table 18: Leading Brands in the US Nasal Aspirators Market (2008): Percentage Breakdown of Retail Value Sales by Brand - Cara, First Years, Gerber, Luv N Care Nuby, Ross, Sunmark, Private Label, and Others (includes corresponding Graph/Chart).....III-10

Table 19: Leading Brands in the US Nasal Aspirators Market (2008): Percentage Breakdown of Retail Volume Sales by Brand - Cara, First Years, Gerber, Luv N Care Nuby, Ross, Sunmark, Private Label, and Others (includes corresponding Graph/Chart).....III-10
1$200
   Table 20: Leading Brands in the US Nasal Sprays Market (2008): Percentage Breakdown of Retail Volume Sales by Brand - Afrin, Afrin No Drip, Primatene Mist, Vicks Sinex, Zicam, and Others (includes corresponding Graph/Chart).....III-11

Table 21: Leading Brands in the US Internal Analgesic Liquids Market (2007): Percentage Breakdown of Retail Value Sales by Brand - Children's Advil, Children's Motrin, Children's Tylenol, Infants' Advil, Infants' Motrin, Motrin, Tylenol, Tylenol Flavor Creator, Tylenol PM, Private Label, and Others (includes corresponding Graph/Chart).....III-11
1$200
   Table 22: Leading Brands in the US Internal Analgesic Liquids Market (2007): Percentage Breakdown of Retail Volume Sales by Brand -Children's Advil, Children's Motrin, Children's Tylenol, Gel Stat, Infants' Advil, Infants' Motrin, Motrin, Tylenol, Tylenol Flavor Creator, Tylenol PM, Private Label, and Others (includes corresponding Graph/Chart).....III-12
Select Intranasal Antihistamines, Oral OTC Antihistamines, and Intranasal
  Corticosteroids in the US Market, as of 2008.....III-12
1$200
   Product Launches.....III-132$125
   Strategic Corporate Developments.....III-153$175
   Key Players.....III-183$175
   B. Market Analytics.....III-21
Table 23: The US Recent Past, Current & Future Analysis for Cold, Cough and Sore Throat Remedies - Annual Sales Figures in US$ Million for Years 2006 through 2015 (includes corresponding Graph/Chart).....III-21
1$200
   A. Market Analysis.....III-22
Outlook.....III-22
OTC Products Market.....III-22
Table 24: Canadian OTC Products Market (2006): Percentage Breakdown of Retail Value Sales by Category - Analgesics, Cold and Cough, Digestives, Nutritional Products, and Others (includes corresponding Graph/Chart).....III-22

Table 25: Canadian OTC Products Market (2006): Percentage Breakdown of Retail Value Sales by Outlet Type - Mass Merchandisers, Food Stores, Drug Stores, and Others (includes corresponding Graph/Chart).....III-22
1$200
   Table 26: Canadian OTC Products Market (2006): Percentage Breakdown of Retail Value Sales by Leading Companies - Bayer Group, Jamieson Laboratories, Johnson & Johnson, Perrigo, Wyeth, and Others (includes corresponding Graph/Chart).....III-23
B. Market Analytics.....III-23
Table 27: Canadian Recent Past, Current & Future Analysis for Cold, Cough and Sore Throat Remedies - Annual Sales Figures in US$ Million for Years 2006 through 2015 (includes corresponding Graph/Chart).....III-23
1$200
   A. Market Analysis.....III-24
Outlook.....III-24
OTC Drugs Market.....III-24
Pharmaceutical Affairs Law.....III-24
1$75
   B. Market Analytics.....III-25
Table 28: Japanese Recent Past, Current & Future Analysis for Cold, Cough and Sore Throat Remedies - Annual Sales Figures in US$ Million for Years 2006 through 2015 (includes corresponding Graph/Chart).....III-25
1$200
   A. Market Analysis.....III-26
Outlook.....III-26
Overview.....III-26
Innovative Packaging Induces Growth.....III-26
OTC Markets Espouse FMCG Market Features.....III-26
1$75
   Market Snippets.....III-271$75
   B. Market Analytics.....III-28
Table 29: European Recent Past, Current & Future Analysis for Cold, Cough and Sore Throat Remedies by Geographic Region - France, Germany, Italy, Spain, UK, and Rest of Europe Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2006 through 2015 (includes corresponding Graph/Chart).....III-28
1$200
   Table 30: European 9-Year Perspective for Cold, Cough and Sore Throat Remedies by Geographic Region - Percentage Breakdown of Dollar Sales for France, Germany, Italy, Spain, UK, and Rest of Europe Markets for the Years 2006, 2009 & 2015 (includes corresponding Graph/Chart).....III-291$200
   A. Market Analysis.....III-30
Outlook.....III-30
Overview.....III-30
1$75
   B. Market Analytics.....III-31
Table 31: French Recent Past, Current & Future Analysis for Cold, Cough and Sore Throat Remedies - Annual Sales Figures in US$ Million for Years 2006 through 2015 (includes corresponding Graph/Chart).....III-31
1$200
   A. Market Analysis.....III-32
Outlook.....III-32
Overview.....III-32
1$75
   B. Market Analytics.....III-33
Table 32: German Recent Past, Current & Future Analysis for Cold, Cough and Sore Throat Remedies - Annual Sales Figures in US$ Million for Years 2006 through 2015 (includes corresponding Graph/Chart).....III-33
1$200
   A. Market Analysis.....III-34
Outlook.....III-34
Overview.....III-34
1$75
   B. Market Analytics.....III-35
Table 33: Italian Recent Past, Current & Future Analysis for Cold, Cough and Sore Throat Remedies - Annual Sales Figures in US$ Million for Years 2006 through 2015 (includes corresponding Graph/Chart).....III-35
1$200
   A. Market Analysis.....III-36
Outlook.....III-36
Overview.....III-36
1$75
   Table 34: The UK Market for Cold and Flu Remedies (2008): Percentage Breakdown of Retail Value Sales by Major Brands - Beechams, Benylin, Lemsip, Nurofen Cold and Flu, Nurses, Private Label, and Others (includes corresponding Graph/Chart).....III-37
Strategic Corporate Developments.....III-37
1$200
   Key Players.....III-381$75
   B. Market Analytics.....III-39
Table 35: The UK Recent Past, Current & Future Analysis for Cold, Cough and Sore Throat Remedies - Annual Sales Figures in US$ Million for Years 2006 through 2015 (includes corresponding Graph/Chart).....III-39
1$200
   A. Market Analysis.....III-40
Outlook.....III-40
Overview.....III-40
1$75
   B. Market Analytics.....III-41
Table 36: Spanish Recent Past, Current & Future Analysis for Cold, Cough and Sore Throat Remedies - Annual Sales Figures in US$ Million for Years 2006 through 2015 (includes corresponding Graph/Chart).....III-41
1$200
   A. Market Analysis.....III-42
Outlook.....III-42
Product Launches.....III-42
1$75
   Strategic Corporate Developments.....III-43
Key Players.....III-43
1$75
   B. Market Analytics.....III-44
Table 37: Rest of Europe Recent Past, Current & Future Analysis for Cold, Cough and Sore Throat Remedies - Annual Sales Figures in US$ Million for Years 2006 through 2015 (includes corresponding Graph/Chart).....III-44
1$200
   A. Market Analysis.....III-45
Outlook.....III-45
Peek into Select Markets.....III-45
Indian Market Overview.....III-45
Shift from Rx to OTC: Viable Solution for Off-Patent Products.....III-45
Complete Conversion of Rx to OTC is Unfeasible.....III-45
1$75
   OTC Retail.....III-46
Impelling Factors.....III-46
Impeding Factors.....III-46
Economic Slowdown Disturbs Pharma Industry Growth.....III-46
Chinese Market Overview.....III-46
1$75
   OTC Drugs Market Gains Momentum.....III-47
Peruvian Market Overview.....III-47
Product Launches.....III-47
1$75
   Strategic Corporate Developments.....III-481$75
   Key Players.....III-492$125
   B. Market Analytics.....III-51
Table 38: Rest of World Recent Past, Current & Future Analysis for Cold, Cough and Sore Throat Remedies - Annual Sales Figures in US$ Million for Years 2006 through 2015 (includes corresponding Graph/Chart).....III-51
1$200
    
 
 


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