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ORGAN AND TISSUE TRANSPLANTATION - A GLOBAL STRATEGIC BUSINESS REPORT   

Research Abstract

This report analyzes the worldwide markets for Organ and Tissue Transplantation by Number of Procedures. The global and other markets (except the US) are analyzed only by Organ Type - Heart, Kidneys, Liver, Pancreas, and Lungs. The US market is analyzed both by Organ Type (Heart, Kidneys, Liver, Pancreas, Lungs, & Intestine) and Tissue Type (Cornea, Heart Valve, Skin Grafts, Vascular Grafts, Bone Marrow, and Bone Grafts). Also, the report further analyzes the US market for Bone Graft Transplantation both by Graft Type (Autologous Graft, Allograft, and Other Materials), and by Application Type (General Orthopedics, Spinal Fusions, and Cranio/Maxillofacial). The report provides separate comprehensive analytics for the US, Canada, Europe, Asia (including Japan), Latin America and Rest of World. Annual estimates and forecasts are provided for the period 2009 through 2015. Also, a six-year historic analysis is provided for these markets. The report profiles 77 companies including many key and niche players such as Abiomed, Inc., Arbios Systems, Inc., Arrow International, Inc., CryoLife, Inc., Exactech, Inc., Fresenius Medical Care AG & Co. KGaA, Forticell Bioscience, Inc., Gambro AB, Genzyme Corporation, Jarvik Heart, Inc., LifeCell Corporation, Medtronic, Inc., MicroMed Cardiovascular, Inc., Organogenesis, Inc., SynCardia Systems, Terumo Corporation, Thoratec Corporation, and WorldHeart Corporation. Market data and analytics are derived from primary and secondary research. Company profiles are mostly extracted from URL research and reported select online sources.

Code : MCP-1572
Price : $4950
Companies : 77
Pages : 423
Date : January 2011
Market Data Tables : 101

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 TABLE OF CONTENTS

  ORGAN AND TISSUE TRANSPLANTATION (Complete Report) Pages : 423   | $4950
 
  1. INTRODUCTION, METHODOLOGY & PRODUCT DEFINITIONS.......16 $295  
   Study Reliability and Reporting Limitations.......1  
   Disclaimers.......2  
   Data Interpretation & Reporting Level.......3
Quantitative Techniques & Analytics.......3
Product Definitions and Scope of Study.......3
Tissue and Organ Transplantation.......3
  
   Bone Graft Transplantation.......4
Product Definitions.......4
Organ Transplantation.......4
Heart Transplantation.......4
  
   Kidney Transplantation.......5
Liver Transplantation.......5
Pancreas Transplantation.......5
Small Intestine Transplantation.......5
Lungs.......5
  
   Tissue Transplantation.......6
Corneal Transplantation.......6
Blood Stem Cell Transplantation.......6
Bone Marrow Transplantation.......6
Heart Valves Transplantation.......6
  
  2. MARKET OVERVIEW.......73 $295  
   A Quick Primer.......7
Current and Future Analysis.......7
1$100
   Demand and Supply Imbalance.......8
Measures to Address Organ Shortage.......8
Cardiac Arrest Death Patients: The Untapped Potential Donors.......8
1$100
   Transplantation Expenses.......91$100
  3. MARKET TRENDS.......10   
   Living Donor Organs on the Rise.......10
Combined Organ Transplantation – Gaining Attention.......10
Increasing Consent Rates – A Key Factor.......10
Transplant Tourism – Creating Brighter Avenues.......10
1$100
   Alliances to Play a Key Role.......11
Graying Population and Chronic Diseases Surge Need for Transplants.......11
Fetal Tissue for Bionic Devices – Assuming Importance.......11
1$100
  4. MAJOR ISSUES IMPACTING TRANSPLANTATION MARKET.......12   
   Organ Rejection – A Major Barrier to Transplantation.......12
Scarcity of Donor Organs – A Stumbling Block in Organ Transplantation.......12
Other Issues for Organ Transplantation.......12
Ethical Concerns in Transplants.......12
1$100
   Bioethical Issues Hinder Organ Donation Process.......13
Lack of Requisite Expertise – Hindering Implantation Process.......13
Corneal Transplantation in Developing Countries: Key Challenges.......13
1$100
  5. PRODUCT OVERVIEW.......1427 $1450  
   Organ and Tissue Transplantation.......14
Organ Transplantation.......14
Heart Transplantation.......14
1$100
   Heart Diseases and Disorders.......15
Post Operative Complications and Consequences of Heart Transplants.......15
Bleeding.......15
Infection.......15
Arrythymia.......15
1$100
   Heart Attack.......16
Coronary Artery Disease.......16
Respiratory Dysfunction.......16
Renal Dysfunction.......16
Graft Rejection and Dysfunction.......16
Death.......16
Kidney Transplantation.......16
1$100
   Kidney Disorders and Diseases.......17
Donor Evaluation.......17
Waiting List.......17
Surgery/Post-Operation.......17
Post-Operative Supervision and Issues.......17
1$100
   Liver Transplantation.......181$100
   Liver Disorders and Diseases.......19
Pancreas Transplantation.......19
1$100
   Post Operative Complications and Consequences of Pancreas Transplants.......20
Small Intestine Transplantation.......20
Intestine Disorders and Diseases.......20
Heart-and-Lung Transplantation.......20
1$100
   Lung Transplantation.......21
Lung Diseases and Disorders.......21
Lung Patients Survival Statistics.......21
1$100
   Tissue Transplantation.......22
Types of Grafts.......22
Autograft.......22
Allograft / Homograft.......22
1$100
   Transplant Tolerance.......23
Isograft.......23
Xenograft.......23
Corneal Transplantation.......23
1$100
   Penetrating Keratoplasty.......24
Lamellar (Non-Penetrating) Keratoplasty.......24
Aftercare.......24
1$100
   Risks Associated with Corneal Transplants.......25
Transplantation Outcomes.......25
Morbidity and Mortality Rates.......25
Alternatives.......25
1$100
   Blood Stem Cells.......26
Peripheral Blood Stem Cell Transplant.......26
Umbilical Cord Blood Stem Cell Transplant.......26
Bone Marrow and Hematopoietic Stem Cells.......26
Bone and Tissue Transplantation.......26
1$100
   Bone Marrow Transplants.......27
Stem Cell Therapy.......27
1$100
   Human Heart Valves.......28
Atrioventricular Valves.......28
Mitral Valve.......28
Tricuspid Valve.......28
Semilunar Valves.......28
Aortic Valve.......28
1$100
   Pulmonic Valve.......29
Pathology of Valves.......29
Prosthetic Heart Valves.......29
Prosthetic Mechanical Valve.......29
1$100
   Advantages.......30
Disadvantages.......30
Prosthetic Biologic Valve.......30
1$100
   Advantages.......31
Disadvantages.......31
Fetal Cells.......31
Fetal Tissue for Transplantation.......31
1$100
   Storage Duration Time.......32
Storage Time Period for Organs and Tissues.......32
Cold Ischemia Time.......32
Transplantation Immunology.......32
Acute Cellular Rejection.......32
1$100
   Chronic Rejection.......33
Post Transplant Observations.......33
Types of Donors.......33
Alive Donors.......33
1$100
   Related Donors.......34
Good Samaritans.......34
Rewarded/Forced Donors.......34
Deceased Donors.......34
Directed / Allocated.......34
1$100
   Organs and Tissues Transplanted by Type of Donor.......35
Organ/Tissue Donation and Eligibility Criteria.......35
1$100
   Factors Considered for Matching Recipients to Donor Organs.......36
Testing .......36
Blood Typing.......36
Tissue Typing.......36
Histocompatibility – A Major Barrier for Organ Transplantation.......36
1$100
   Transplantation – Safety Requirements.......371$100
   Waiting List.......38
Active Waiting List Patients.......38
Inactive Waiting List Patients.......38
History.......38
2$200
   Major Milestones in Organ Transplantation.......401$100
  6. ARTIFICIAL ORGANS.......419 $595  
   Artificial Organs Revolutionize Medical Technology Industry.......41
Artificial Organs.......41
Categorization of Artificial Organs.......41
1$100
   External Artificial Organs.......42
Internal or Implantable Artificial Devices.......42
Artificial Heart.......42
Total Artificial Heart (TAH).......42
Ventricle Assist Device (VAD).......42
Right Ventricular Assist Systems (RVAS).......42
Left Ventricular Assist Systems (LVAS).......42
1$100
   Various Ventricle Assist Devices Approved in the Recent Past.......431$100
   Artificial Kidney (Dialyzer).......44
Limitations of Artificial Kidney.......44
Artificial Liver.......44
Various Liver Assist Devices.......44
1$100
   Categorization of Liver Devices.......45
Mechanical Systems.......45
Bio-Artificial Systems.......45
Artificial Pancreas.......45
Artificial Lungs (Oxygenator).......45
1$100
   Types of Artificial Lung.......46
Artificial Cornea.......46
Keratoprostheses.......46
Tissue Engineered Corneas.......46
Artificial Skin/Skin Replacement Products.......46
AlloDerm Regenerative Tissue Matrix.......46
Apligraf.......46
1$100
   Cymetra Micronized AlloDerm Tissue.......47
Dermagraft.......47
Epicel .......47
Integra Products.......47
OrCel .......47
TransCyte.......47
1$100
   Core Competitive Factors.......48
Market Outlook for Artificial Organs.......48
2$200
  7. PRESERVATION SOLUTIONS & IMMUNOSUPPRESSANT DRUGS.......506 $495  
   Organ Preservation Solutions.......50
Celsior Solution.......50
Collins Solution.......50
Euro Collins Solution.......50
Custodiol® HTK Solution.......50
Hypothermosol.......50
1$100
   ViaSpan.......51
Immunosuppressant Drugs.......51
Antibody Products for Treatment of Organ Transplant Rejection.......51
Antithymocyte Globulin.......51
ATGAM.......51
1$100
   Campath/MabCampath.......52
Thymoglobulin.......52
Therapeutic Antibody Products.......52
Antiproliferative Agents.......52
Azathioprine.......52
CellCept.......52
Certican.......52
1$100
   Myfortic.......53
Calcineurin Inhibitors.......53
Cyclosporine.......53
Gengraf.......53
Neoral.......53
Pulminiq.......53
Tacrolimus.......53
1$100
   Prograf.......54
TOR Inhibitors.......54
Side Effects of Immunosuppression Therapy.......54
Select Immunosuppressant Drug Players.......54
Astellas Pharma US, Inc. (USA).......54
F.Hoffmann-La Roche Ltd. (Switzerland).......54
1$100
   Novartis AG (Switzerland).......55
Wyeth (USA).......55
1$100
  8. REGULATORY ENVIRONMENT.......565 $395  
   Transplant Center.......56
Organ Procurement Organization (OPO).......56
Health Resources and Services Administration (HRSA).......56
Division of Transplantation (DoT).......56
United Network for Organ Sharing (UNOS).......56
Organ Procurement and Transplantation Network (OPTN).......56
1$100
   University Renal Research and Education Association (URREA).......57
Scientific Registry of Transplant Recipients (SRTR).......57
Funding Sources.......57
Patient Education and Advocacy Organizations.......57
1$100
   Legal Framework for Transplantation.......58
Legislation Covering Organ Transplant.......58
1$100
   Organ Transplantation and Ethics.......591$100
   Regulations Governing Artificial Organs.......601$100
  9. PRODUCT DEVELOPMENT/INNOVATIONS.......613 $295  
   Dr. Reddy's to Launch Tacrolimus Capsules in US.......61
ApaTech® Unveils Actifuse® MIS Bone Graft Delivery System.......61
DePuy Spine Introduces HEALOS® Fx Injectable Bone Graft Replacement.......61
1$100
   Watson Laboratories Receives FDA Approval for Tacrolimus 5 mg.......62
RTI Biologics Introduces Osteochondral Allograft in San Francisco.......62
Pluristem Develops New Cell Graft for Cancer Patients.......62
1$100
   CryoLife Develops Cryopreserved Orthopaedic Tissues Implants.......63
Japanese Innovators Develop New Prognostic Scoring Model for Liver Transplants.......63
EUREKA project E! 2674 MIDAS Develops New Test to Improve Graft Survival.......63
1$100
  10. RECENT INDUSTRY ACTIVITY.......644 $395  
   International Stem Cell Inks Partnership Deal with Sankara Nethralaya.......64
BGS Global Hospitals Inaugurates New Multi-Organ Transplants Center in India.......64
Vietnamese Ministry of Health to Establish Organ Transplant Coordination
  Center.......64
Novartis Secures US FDA Approval for Zortress Oral Tablets.......64
1$100
   Humacyte Enters into Strategic Alliance with Xcellerex.......65
Osteotech Signs Agreement with Community Tissue Services.......65
Tissue Banks International Enters into a Partnership with Northwest Tissue
  Services.......65
1$100
   Roche Secures FDA Approval for Valcyte.......66
Astellas Pharma Secures FDA Clearance for Prograf and MMF Drug Combination.......66
Astellas Pharma Receives Additional Approval for Prograf.......66
Novadaq® Obtains US FDA Approval for SPY® System.......66
1$100
   St. Jude Medical’s Heart Valve Obtains US FDA Approval.......67
Zimmer and Tutogen Expand Distribution Partnership.......67
1$100
  11. CORPORATE ACTIVITY IN THE RECENT PAST- A PERSPECTIVE BUILDER.......6811 $950  
   Leman Cardiovascular Acquires Hancock Jaffe Laboratories.......68
Nabi Acquires Commercialization Rights of ATG-Fresenius S for North America.......68
Cytopia and Novartis Ink Research Collaboration and Global License Agreement.......68
1$100
   ZLB Behring Inks Agreement with MedImmune.......69
Japanese Team To Perform Liver Transplants in Hyderabad.......69
Nabi Bags Approval for HB Intravenous in Liver Transplant Patients.......69
Schering-Plough Announces PROTECT study Initiation.......69
Allegheny General Hospital To Establish Adult Liver Transplantation Center in
  Oakland.......69
1$100
   Global Hospitals to Setup an Organ Transplant Center in Kolkata.......70
GCC to Establish Organ Transplant Center.......70
Delhi-Based Hospital Offers Help in Setting Up of Liver Transplant Center in
  Lahore.......70
Kaiser To Shut Down Kidney Transplant Center.......70
Abiomed Obtains FDA Approval for Selling Artificial Hearts.......70
Astellas Bags FDA Approval to Use Prograf in Heart Transplant Patients.......70
1$100
   New York State Department of Health Approves Program for Kidney Transplant for Queen’s
  Community.......71
National Heart Institute Conducts First Double Lung Transplant in Malaysia.......71
The Netherlands Obtains Orphan Drug Designations for Treatment of DGF.......71
Papworth Transplants First Beating Human Heart in the UK.......71
1$100
   Enzon to Return ATG-Fresenius S Rights to Fresenius Biotech.......72
Schering-Plough to Conduct ‘PROTECT’ Study.......72
Community Tissue Services Selects NOVA 2200 Supercritical Carbon Dioxide Sterilization
  Technology.......72
1$100
   CryoLife Inks Agreement with The Magdi Yacoub Institute to Enhance Xenografts in Human
  Transplantation.......73
ReGen Inks Exclusive Marketing Deals with Polymedic and Xmedica.......73
University of California-Irvine Announces Closure of Liver-Transplantation
  Program.......73
1$100
   Swedish Health Services Bags Approval for Liver Transplant Program.......74
New Organ Transplant Research Center in South Korea.......74
Child Lung Transplant Unit to be opened in Melbourne Hospital.......74
Narayana Hrudayalaya Health City Establishes Exclusive Organ Transplant
  Hospital.......74
Liver Transplant Facility in Delhi Region.......74
First Liver Transplant Research Institute in China.......74
1$100
   PIMS to establish Liver Transplant Unit.......75
Liver Transplant Programme in Pakistan.......75
Isotechnika Gains FDA Approval.......75
FDA Offers Approval for Brain Stem Cell Transplant Trial.......75
Methodist Specialty and Transplant Hospital Gains Approval to Execute Liver
  Transplants.......75
Cubist Pharma Enters into Licensing Agreement with XTL Biopharmaceuticals.......75
1$100
   Jackson Memorial Receives Approval from the U.S. Centers for Medicare and Medicaid
  Services.......76
Royal Perth Hospital to Open Lung Transplant Unit in Perth.......76
Mater Hospital Opens Lung Transplant Unit in Dublin.......76
1$100
   Genzyme Makes a Synergistic Purchase of Ilex Oncology.......77
NIAID Sets Up Clinical Consortium to Enhance Organ Transplants Success.......77
Chiron files NDA for Pulminiq Inhalation Solution.......77
Roche Acquires IL-15 Antagonist.......77
1$100
   Genzyme Completes Acquisition of SangStat.......781$100
  12. FOCUS O SELECT GLOBAL PLAYERS.......798 $595  
   Abiomed, Inc. (USA).......79
Arbios Systems, Inc. (USA).......79
1$100
   Arrow International, Inc. (USA).......80
CryoLife, Inc.(USA).......80
Exactech, Inc. (USA).......80
1$100
   Fresenius Medical Care AG & Co. KGaA (Germany).......81
Forticell Bioscience, Inc. (USA).......81
Gambro AB (Sweden).......81
1$100
   Genzyme Corporation (USA).......82
Jarvik Heart, Inc. (USA).......82
1$100
   LifeCell Corporation (USA).......83
Medtronic, Inc. (USA).......83
1$100
   MicroMed Cardiovascular, Inc. (USA).......84
Organogenesis, Inc. (USA).......84
SynCardia Systems (USA).......84
1$100
   Terumo Corporation (Japan).......85
Thoratec Corporation (USA).......85
WorldHeart Corporation (USA).......85
2$200
  13. GLOBAL MARKET PERSPECTIVE.......87   
   Table 1: World Recent Past, Current & Future Market Analysis for Organ Transplantation by Geographic Region – US, Canada, Europe, Asia (including Japan), Latin America and Rest of World Independently Analyzed by Number of Procedures for Years 2009 through 2015 (includes corresponding Graph/Chart).......871$350
   Table 2: World Historic Review for Organ Transplantation by Geographic Region – US, Canada, Europe, Asia (including Japan), Latin America and Rest of World Independently Analyzed by Number of Procedures for Years 2003 through 2008 (includes corresponding Graph/Chart).......881$350
   Table 3: World 11-Year Perspective for Organ Transplantation by Geographic Region – Percentage Breakdown of Number of Procedures for US, Canada, Europe, Asia (including Japan), Latin America and Rest of World Markets for Years 2005, 2010 & 2015 (includes corresponding Graph/Chart).......891$350
   Table 4: World Recent Past, Current & Future Market Analysis for Heart Transplantation by Geographic Region – US, Canada, Europe, Asia (including Japan), Latin America and Rest of World Independently Analyzed by Number of Procedures for Years 2009 through 2015 (includes corresponding Graph/Chart).......901$350
   Table 5: World Historic Review for Heart Transplantation by Geographic Region – US, Canada, Europe, Asia (including Japan), Latin America and Rest of World Independently Analyzed by Number of Procedures for Years 2003 through 2008 (includes corresponding Graph/Chart).......911$350
   Table 6: World 11-Year Perspective for Heart Transplantation by Geographic Region – Percentage Breakdown of Number of Procedures for US, Canada, Europe, Asia (including Japan), Latin America and Rest of World Markets for Years 2005, 2010 & 2015 (includes corresponding Graph/Chart).......921$350
   Table 7: World Recent Past, Current & Future Market Analysis for Kidney Transplantation by Geographic Region – US, Canada, Europe, Asia (including Japan), Latin America and Rest of World Independently Analyzed by Number of Procedures for Years 2009 through 2015 (includes corresponding Graph/Chart).......931$350
   Table 8: World Historic Review for Kidney Transplantation by Geographic Region – US, Canada, Europe, Asia (including Japan), Latin America and Rest of World Independently Analyzed by Number of Procedures for Years 2003 through 2008 (includes corresponding Graph/Chart).......941$350
   Table 9: World 11-Year Perspective for Kidney Transplantation by Geographic Region – Percentage Breakdown of Number of Procedures for US, Canada, Europe, Asia (including Japan), Latin America and Rest of World Markets for Years 2005, 2010 & 2015 (includes corresponding Graph/Chart).......951$350
   Table 10: World Recent Past, Current & Future Market Analysis for Liver Transplantation by Geographic Region – US, Canada, Europe, Asia (including Japan), Latin America and Rest of World Independently Analyzed by Number of Procedures for Years 2009 through 2015 (includes corresponding Graph/Chart).......961$350
   Table 11: World Historic Review for Liver Transplantation by Geographic Region – US, Canada, Europe, Asia (including Japan), Latin America and Rest of World Independently Analyzed by Number of Procedures for Years 2003 through 2008 (includes corresponding Graph/Chart).......971$350
   Table 12: World 11-Year Perspective for Liver Transplantation by Geographic Region – Percentage Breakdown of Number of Procedures for US, Canada, Europe, Asia (including Japan), Latin America and Rest of World Markets for Years 2005, 2010 & 2015 (includes corresponding Graph/Chart).......981$350
   Table 13: World Recent Past, Current & Future Market Analysis for Pancreas Transplantation by Geographic Region – US, Canada, Europe, Asia (including Japan), Latin America and Rest of World Independently Analyzed by Number of Procedures for Years 2009 through 2015 (includes corresponding Graph/Chart).......991$350
   Table 14: World Historic Review for Pancreas Transplantation by Geographic Region – US, Canada, Europe, Asia (including Japan), Latin America and Rest of World Independently Analyzed by Number of Procedures for Years 2003 through 2008 (includes corresponding Graph/Chart).......1001$350
   Table 15: World 11-Year Perspective for Pancreas Transplantation by Geographic Region – Percentage Breakdown of Number of Procedures for US, Canada, Europe, Asia (including Japan), Latin America and Rest of World Markets for Years 2005, 2010 & 2015 (includes corresponding Graph/Chart).......1011$350
   Table 16: World Recent Past, Current & Future Market Analysis for Lung Transplantation by Geographic Region – US, Canada, Europe, Asia (including Japan), Latin America and Rest of World Independently Analyzed by Number of Procedures for Years 2009 through 2015 (includes corresponding Graph/Chart).......1021$350
   Table 17: World Historic Review for Lung Transplantation by Geographic Region – US, Canada, Europe, Asia (including Japan), Latin America and Rest of World Independently Analyzed by Number of Procedures for Years 2003 through 2008 (includes corresponding Graph/Chart).......1031$350
   Table 18: World 11-Year Perspective for Lung Transplantation by Geographic Region – Percentage Breakdown of Number of Procedures for US, Canada, Europe, Asia (including Japan), Latin America and Rest of World Markets for Years 2005, 2010 & 2015 (includes corresponding Graph/Chart).......1041$350
   Table 19: World Recent Past, Current & Future Market Analysis for Corneal Transplantation by Geographic Region – US, Canada, Europe, Asia (including Japan), Latin America and Rest of World Independently Analyzed by Number of Procedures for Years 2009 through 2015 (includes corresponding Graph/Chart).......1051$350
   Table 20: World Historic Review for Corneal Transplantation by Geographic Region – US, Canada, Europe, Asia (including Japan), Latin America and Rest of World Independently Analyzed by Number of Procedures for Years 2003 through 2008 (includes corresponding Graph/Chart).......1061$350
   Table 21: World 11-Year Perspective for Corneal Transplantation by Geographic Region – Percentage Breakdown of Number of Procedures for US, Canada, Europe, Asia (including Japan), Latin America and Rest of World Markets for Years 2005, 2010 & 2015 (includes corresponding Graph/Chart).......1071$350
  14. THE UNITED STATES.......10843 $4450  
   A. Market Analysis.......108
Current and Future Analysis.......108
Analysis by Value Sales.......108
Liver Transplantation Sustains Dominance in Value Sales.......108
Skin Grafts Takes the Largest Chunk in Tissue Transplantations.......108
Analysis by Number of Procedures.......108
Kidney Transplants Represent the Largest, While Intestine Transplants to Register
  Fastest Growth.......108
1$100
   Skin Grafts – Largest and Fastest Growing Tissue Segment.......109
Bone Graft Procedure Volume by Graft Type and Application.......109
A Few Organ Transplant Facts and Figures in the US.......109
Sources of Donor Organs.......109
1$100
   Table 22: US Kidney Donations by Donor Type - Cadaveric and Living for Years 2003 through 2008 (includes corresponding Graph/Chart).......110

Table 23: US Liver Donations by Donor Type - Cadaveric and Living for Years 2003 through 2008 (includes corresponding Graph/Chart).......110
1$350
   Table 24: US Heart Donations by Cadaveric Donor Type for Years 2003 through 2008 (includes corresponding Graph/Chart).......111

Table 25: US Lung Donations by Donor Type - Cadaveric and Living for Years 2003 through 2008 (includes corresponding Graph/Chart).......111
1$350
   Table 26: US Pancreas Donations by Donor Type - Cadaveric and Living for Years 2003 through 2008 (includes corresponding Graph/Chart).......112

Table 27: US Intestine Donations by Donor Type - Cadaveric and Living for Years 2003 through 2008 (includes corresponding Graph/Chart).......112
Key Market Trends.......112
Innovative Means of Organ Procurement to Increase Organ Donations.......112
1$350
   A New Technique to Enhance and Extend Kidney Transplants.......113
California Stands Up Against Insurance on HIV Patients’ Transplantation.......113
Awareness Programs to Address Shortage of Minority Donors.......113
Organs and Tissues on A Recovery Spree.......113
1$100
   Unexamined Human Tissue Transplants – A Major Threat.......114
Defective Medical Implants – A Health Hazard.......114
Eye Infections from Usage of MoistureLoc Leads to Corneal Transplants.......114
1$100
   Incidence of Organ Transplants.......115
Table 28: Incidence of Organ Transplant per 1 Million Population in the US by Type - Kidney, Liver, Heart, Lung, Pancreas, Intestine, and Heart-Lung Transplants, for the Year 2003 through 2008 (includes corresponding Graph/Chart).......115

Table 29: Incidence of Organ Transplants (Kidney, Liver, Heart, Lung, Pancreas, Intestine, and Heart- Lung) per 1 Million Population in the US by Recipient Race (White, African American, Asian, Hispanic, and Other) for 2008 (includes corresponding Graph/Chart).......115
1$350
   Table 30: Incidence of Organ Transplants (Kidney, Liver, Heart, Lung, Pancreas, Intestine, and Heart-Lung) per 1 Million Population in the US by Recipient Gender (Male, and Female) for 2008 (includes corresponding Graph/Chart).......116

Table 31: Incidence of Organ Transplants (Kidney, Liver, Heart, Lung, Pancreas, Intestine, and Heart-Lung) per 1 Million Population in the US by Recipient Age (65+ Years, 50-64 Years, 35-49 Years, 18-34 Years, 11-17 Years, 6-10 Years, 1-5 Years, <1 Year) for 2008 (includes corresponding Graph/Chart).......116
1$350
   Heart Transplantation.......117
Table 32: Heart Transplant Life Expectancy in the US (2009): As of 2009 (includes corresponding Graph/Chart).......117
Lung Transplantation.......117
1$350
   Heart-Lung Transplantation.......118
Waiting List.......118
Table 33: Waiting List of Patients As of July 2010 (includes corresponding Graph/Chart).......118
1$350
   Table 34: Waiting List of Active and Inactive Patients for the Year 2008 (includes corresponding Graph/Chart).......119
Waiting List for Heart Transplants.......119
1$350
   Table 35: Waiting List of Active Patients for Heart for Years 2000 to 2008 (includes corresponding Graph/Chart).......120
Categorized by Diseases.......120
Categorized by Age.......120
Categorized by Race.......120
Death Rates on the Waiting Lists.......120
1$350
   Kidney Transplantation Waiting List.......121
Categorized by Age.......121
Categorized by Race.......121
Waiting List for Liver Transplants.......121
Categorized by Age.......121
1$100
   Categorized by Race.......122
Categorized by Gender.......122
Categorized by Diseases.......122
Categorized by Re-Transplant Necessity.......122
Pancreas Transplant Waiting List.......122
Simultaneous Pancreas Kidney Transplantation Waiting List.......122
Waiting List for Lung Transplants.......122
1$100
   Categorized by Age.......123
Categorized by Primary Diagnoses.......123
Categorized by Gender and Ethnic Makeup.......123
Waiting List for Intestine Transplants.......123
Death Rates on Waiting List.......123
1$100
   Patient Survival Rate.......124
Table 36: Unadjusted Patient Survival Rate (*) by Organ Type for 1-Year and 5-Years (includes corresponding Graph/Chart).......124
1$350
   Multi-Organ Transplant Gaining Momentum.......125
Table 37: Multi-Organ Transplants in the US: 2005-2008 (includes corresponding Graph/Chart).......125
Immunosuppression Therapy.......125
Immunosuppression Therapy for Heart Transplant Recipients.......125
1$350
   Table 38: Usage Rates of Major Immunosuppressants at Discharge by Organ Type for the Year 2008 (includes corresponding Graph/Chart).......126
Immunosuppression Therapy for Kidney Transplant Recipients.......126
Immunosuppression Therapy for Pancreas Transplants.......126
Immunosuppression Therapy for Lung Transplant Recipients.......126
1$350
   Table 39: Usage Rates of Induction Drugs For Lung Transplant Recipients in 2008 (includes corresponding Graph/Chart).......127
Immunosuppression Therapy, Following Bone Marrow Transplantation.......127
Table 40: US Recent Past, Current & Future Market Analysis for Immunosuppressive Drug Therapy Following Bone Marrow Transplantation by Category – For GVHD and Maintenance Independently Analyzed with Annual Sales Figures in US$ Million for Years 2009 through 2015 (includes corresponding Graph/Chart).......127
1$350
   Table 41: US Historic Review for Immunosuppressive Drug Therapy Following Bone Marrow Transplantation by Category – For GVHD and Maintenance Independently Analyzed with Annual Sales Figures in US$ Million for Years 2003 through 2008 (includes corresponding Graph/Chart).......128

Table 42: US 11-Year Perspective for Immunosuppressive Drug Therapy Following Bone Marrow Transplantation by Category – Percentage Breakdown of Dollar Sales For GVHD and Maintenance Independently Analyzed with Annual Sales Figures in US$ Million for Years 2005, 2010, and 2015.......128
1$350
   Immunosuppression Therapy, Following Blood Stem Cell Transplantation.......129
Table 43: US Recent Past, Current & Future Market Analysis for Immunosuppressive Drug Therapy Following Blood Stem Cell Transplantation by Category – For GVHD and Maintenance Independently Analyzed with Annual Sales Figures in US$ Million for Years 2009 through 2015 (includes corresponding Graph/Chart).......129
1$350
   Table 44: US Historic Review for Immunosuppressive Drug Therapy Following Blood Stem Cell Transplantation by Category – For GVHD and Maintenance Independently Analyzed with Annual Sales Figures in US$ Million for Years 2003 through 2008 (includes corresponding Graph/Chart).......130

Table 45: US 11-Year Perspective for Immunosuppressive Drug Therapy Following Blood Stem Cell Transplantation by Category – Percentage Breakdown of Dollar Sales For GVHD and Maintenance Independently Analyzed with Annual Sales Figures in US$ Million for Years 2005, 2010, and 2015.......130
The United Network for Organ Sharing.......130
1$350
   The American Association of Tissue Banks (AATB).......131
Accredited Banks from Select US States.......131
2$200
   Eye Banks from Select US States.......1331$100
   Number of Transplant Center Programs.......134
Table 46: Number of Transplant Center Programs for the Years 1990, 1997 and 2000 (includes corresponding Graph/Chart).......134
1$350
   Table 47: Average Number of Transplants Per Program for the Years 1990, 1997 and 2000 (includes corresponding Graph/Chart).......1351$350
   B. Market Analytics.......136
Table 48: US Recent Past, Current & Future Market Analysis for Organ Transplantation by Organ Type – Heart, Kidney, Liver, Pancreas, Lung and Intestine Independently Analyzed with Annual Sales Figures in US$ Million for Years 2009 through 2015 (includes corresponding Graph/Chart).......136
1$350
   Table 49: US Historic Review for Organ Transplantation by Organ Type – Heart, Kidney, Liver, Pancreas, Lung and Intestine Independently Analyzed with Annual Sales Figures in US$ Million Years 2003 through 2008 (includes corresponding Graph/Chart).......1371$350
   Table 50: US 11-Year Perspective for Organ Transplantation by Organ Type – Percentage Breakdown of Dollar Sales for Heart, Kidney, Liver, Pancreas, Lung and Intestine Markets for Years 2005, 2010 & 2015 (includes corresponding Graph/Chart).......1381$350
   Table 51: US Recent Past, Current & Future Market Analysis for Tissue Transplantation by Tissue Type – Cornea, Heart Valves and Skin Grafts Independently Analyzed with Annual Sales Figures in US$ Million for Years 2009 through 2015 (includes corresponding Graph/Chart).......1391$350
   Table 52: US Historic Review for Tissue Transplantation by Tissue Type – Cornea, Heart Valves and Skin Grafts Independently Analyzed with Annual Sales Figures in US$ Million for Years 2003 through 2008 (includes corresponding Graph/Chart).......140

Table 53: US 11-Year Perspective for Tissue Transplantation by Tissue Type – Percentage Breakdown of Dollar Sales for Cornea, Heart Valves and Skin Grafts Markets for Years 2005, 2010 & 2015 (includes corresponding Graph/Chart).......140
1$350
   By Number of Procedures.......141
Table 54: US Recent Past, Current & Future Market Analysis for Organ Transplantation by Organ Type – Heart, Kidney, Liver, Pancreas, Lung and Intestine Independently Analyzed by Number of Procedures for Years 2009 through 2015 (includes corresponding Graph/Chart).......141
1$350
   Table 55: US Historic Review for Organ Transplantation by Organ Type – Heart, Kidney, Liver, Pancreas, Lung and Intestine Independently Analyzed by Number of Procedures for Years 2003 through 2008 (includes corresponding Graph/Chart).......1421$350
   Table 56: US 11-Year Perspective for Organ Transplantation by Organ Type – Percentage Breakdown of Number of Procedures for Heart, Kidney, Liver, Pancreas, Lung and Intestine Markets for Years 2005, 2010 & 2015 (includes corresponding Graph/Chart).......1431$350
   Table 57: US Recent Past, Current & Future Market Analysis for Tissue Transplantation by Tissue Type – Cornea, Heart Valves, Skin Grafts, Vascular Grafts, Bone Marrow and Bone Grafts Independently Analyzed by Number of Procedures for Years 2009 through 2015 (includes corresponding Graph/Chart).......1441$350
   Table 58: US Historic Review for Tissue Transplantation by Tissue Type – Cornea, Heart Valves, Skin Grafts, Vascular Grafts, Bone Marrow and Bone Grafts Independently Analyzed by Number of Procedures for Years 2003 through 2008 (includes corresponding Graph/Chart).......1451$350
   Table 59: US 11-Year Perspective for Tissue Transplantation by Tissue Type – Percentage Breakdown of Number of Procedures for Cornea, Heart Valves, Skin Grafts, Vascular Grafts, Bone Marrow and Bone Grafts Markets for Years 2005, 2010 & 2015 (includes corresponding Graph/Chart).......1461$350
   Table 60: US Recent Past, Current & Future Market Analysis for Bone Graft Transplantation by Graft Type – Autologous Graft, Allograft and Other Materials Independently Analyzed by Number of Procedures for Years 2009 through 2015 (includes corresponding Graph/Chart).......1471$350
   Table 61: US Historic Review for Bone Graft Transplantation by Graft Type – Autologous Graft, Allograft and Other Materials Independently Analyzed by Number of Procedures for Years 2003 through 2008 (includes corresponding Graph/Chart).......148

Table 62: US 11-Year Perspective for Bone Graft Transplantation by Graft Type – Percentage Breakdown of Number of Procedures for Autologous Graft, Allograft and Other Materials Markets for Years 2005, 2010 & 2015 (includes corresponding Graph/Chart).......148
1$350
   Table 63: US Recent Past, Current & Future Market Analysis for Bone Graft Transplantation by Application – General Orthopedics, Spinal Fusions and Cranio/Maxillofacial Independently Analyzed by Number of Procedures for Years 2009 through 2015 (includes corresponding Graph/Chart).......1491$350
   Table 64: Historic Review for Bone Graft Transplantation by Application – General Orthopedics, Spinal Fusions and Cranio/ Maxillofacial Independently Analyzed by Number of Procedures for Years 2003 through 2008 (includes corresponding Graph/Chart).......150

Table 65: US 11-Year Perspective for Bone Graft Transplantation by Application – Percentage Breakdown of Number of Procedures for General Orthopedics, Spinal Fusions and Cranio/Maxillofacial Markets for Years 2005, 2010 & 2015 (includes corresponding Graph/Chart).......150
1$350
  15. CANADA.......1516 $1450  
   A. Market Analysis.......151
Current and Future Analysis.......151
Canadians More Receptive to Organ Transplants.......151
Waiting List.......151
1$100
   Table 66: Canadian Patients (Active and Inactive) on Waiting List by Organ Type for 2009 and 1H 2010 (*)(includes corresponding Graph/Chart).......152
Organ Donation.......152
Table 67: Canadian Organ Donations by Donor Type - Cadaveric and Living for Years 2003 through 2007 (includes corresponding Graph/Chart).......152
1$350
   Success Rate of Organ Transplants.......153
Table 68: Success Rate of Organ Transplants After 1-Year (includes corresponding Graph/Chart).......153
1$350
   B. Market Analytics.......154
Table 69: Canadian Recent Past, Current & Future Market Analysis for Organ Transplantation by Organ Type – Heart, Kidney, Liver, Pancreas and Lung Independently Analyzed by Number of Procedures for Years 2009 through 2015 (includes corresponding Graph/Chart).......154
1$350
   Table 70: Canadian Historic Review for Organ Transplantation by Organ Type – Heart, Kidney, Liver, Pancreas and Lung Independently Analyzed by Number of Procedures for Years 2003 through 2008 (includes corresponding Graph/Chart).......1551$350
   Table 71: Canadian 11-Year Perspective for Organ Transplantation by Organ Type – Percentage Breakdown of Number of Procedures for Heart, Kidney, Liver, Pancreas and Lung Markets for Years 2005, 2010 & 2015 (includes corresponding Graph/Chart).......1561$350
  16. EUROPE.......1579 $2450  
   A. Market Analysis.......157
Current and Future Analysis.......157
Table 72: Number of Organ Transplants in Select European Countries by Organ: 2009 (includes corresponding Graph/Chart).......157
1$350
   Table 73: Number of Deceased Organ Donors in Select European Countries for 2008 & 2009 (includes corresponding Graph/Chart).......158
Focus on Select Regions.......158
The United Kingdom.......158
UK Organ Transplantation System: An Overview.......158
Organ Transplantation in the UK.......158
1$350
   Table 74: UK Organ Transplantations for the Years 2007 and 2008 (includes corresponding Graph/Chart).......159

Table 75: Waiting List (Active and Inactive) by Organ in the UK for the Years 2007 and 2008 (includes corresponding Graph/Chart).......159
1$350
   Corneal Transplantation in the UK.......160
Bladder Transplantation: A Roaring Success.......160
Spain.......160
Organ Transplantation in Spain.......160
1$100
   France.......161
Table 76: Organ Transplantations in France for the Years 2006 through 2008 (includes corresponding Graph/Chart).......161
1$350
   Table 77: Waiting List (Active and Inactive) by Organ in France for the Years 2006 through 2008 (includes corresponding Graph/Chart).......162
Italy.......162
Surge in Organ Transplants.......162
Russia.......162
Organ Transplantations Show a Downward Trend in Russia.......162
Turkey.......162
Akdeniz University – A World-Renowned Transplantation Center.......162
1$350
   B. Market Analytics.......163
Table 78: European Recent Past, Current & Future Market Analysis for Organ Transplantation by Organ Type – Heart, Kidney, Liver, Pancreas and Lung Independently Analyzed by Number of Procedures for Years 2009 through 2015 (includes corresponding Graph/Chart).......163
1$350
   Table 79: European Historic Review for Organ Transplantation by Organ Type – Heart, Kidney, Liver, Pancreas and Lung Independently Analyzed by Number of Procedures for Years 2003 through 2008 (includes corresponding Graph/Chart).......1641$350
   Table 80: European 11-Year Perspective for Organ Transplantation by Organ Type – Percentage Breakdown of Number of Procedures for Heart, Kidney, Liver, Pancreas and Lung Markets for Years 2005, 2010 & 2015 (includes corresponding Graph/Chart).......1651$350
  17. ASIA.......16610 $2450  
   A. Market Analysis.......166
Current & Future Analysis.......166
Focus on Select Regions.......166
Australia.......166
Key Facts on Organ and Tissue Transplantation in Australia.......166
1$100
   Australia Registers Highest Success Rate in Transplantation.......167
Table 81: Organ Transplantation in Australia by Organ Type: 2008 (includes corresponding Graph/Chart).......167

Table 82: Organ Transplant Waiting List by Organ Type: As of January 2010 (includes corresponding Graph/Chart).......167
Kidney Transplantation Snapshots.......167
1$350
   Organ Donor Register.......168
China.......168
Organ Transplantations in China: Year 2005 & 2006 in Review.......168
Transplantation Tourism in China.......168
Low Transplant Success Rate Due to Unskilled Professionals.......168
1$100
   Cost Effective Transplant Procedures Lure Foreign Patients.......169
Illegal Activities for Harvesting Organs in China.......169
Regulations on Organ Transplantation.......169
1$100
   Regulations on Brain Death.......170
India.......170
Overview of Renal Transplantation.......170
1$100
   Transplantation Expenses in India.......171
Indian Government to Amend Organ Transplantation Rules.......171
Singapore.......171
Awareness Programs to Increase Living Kidney Donations in Singapore.......171
1$100
   Taiwan.......172
Taiwan Competes with the US in Kidney and Liver Transplant Survival Rates.......172
1$100
   B. Market Analytics.......173
Table 83: Asia Recent Past, Current & Future Market Analysis for Organ Transplantation by Organ Type – Heart, Kidney, Liver, Pancreas and Lung Independently Analyzed by Number of Procedures for Years 2009 through 2015 (includes corresponding Graph/Chart).......173
1$350
   Table 84: Asia Historic Review for Organ Transplantation by Organ Type – Heart, Kidney, Liver, Pancreas and Lung Independently Analyzed by Number of Procedures for Years 2003 through 2008 (includes corresponding Graph/Chart).......1741$350
   Table 85: Asia 11-Year Perspective for Organ Transplantation by Organ Type – Percentage Breakdown of Number of Procedures for Heart, Kidney, Liver, Pancreas and Lung Markets for Years 2005, 2010 & 2015 (includes corresponding Graph/Chart).......1751$350
  18. LATIN AMERICA.......1764 $950  
   A. Market Analysis.......176
Current & Future Analysis.......176
Brazil – A Major Transplant Market.......176
1$100
   B. Market Analytics.......177
Table 86: Latin American Recent Past, Current & Future Market Analysis for Organ Transplantation by Organ Type – Heart, Kidney, Liver, Pancreas and Lung Independently Analyzed by Number of Procedures for Years 2009 through 2015 (includes corresponding Graph/Chart).......177
1$350
   Table 87: Latin American Historic Review for Organ Transplantation by Organ Type – Heart, Kidney, Liver, Pancreas and Lung Independently Analyzed by Number of Procedures for Years 2003 through 2008 (includes corresponding Graph/Chart).......1781$350
   Table 88: Latin American 11-Year Perspective for Organ Transplantation by Organ Type – Percentage Breakdown of Number of Procedures for Heart, Kidney, Liver, Pancreas and Lung Markets for Years 2005, 2010 & 2015 (includes corresponding Graph/Chart).......1791$350
  19. REST OF WORLD.......1808 $2450  
   A. Market Analysis.......180
Current & Future Analysis.......180
Kuwait – A Rapidly Emerging ‘Third World’ Country in Organ Transplants.......180
South Africa.......180
Key Statistical Findings on Organ and Cornea Transplants.......180
Table 89: Number of Organ and Cornea Transplants in South Africa for Years 2005 through 2009 (includes corresponding Graph/Chart).......180
1$350
   Table 90: Number of Organ Transplants (Excluding Cornea) in South Africa by Organ for Years 2008 & 2009 (includes corresponding Graph/Chart).......181

Table 91: Number of Organ Transplants in Adult Patients in South Africa by Organ for yeas 2008 & 2009 (includes corresponding Graph/Chart).......181
1$350
   Table 92: Number of Organ Transplants in Adolescent Patients in South Africa by Organ for Years 2008 & 2009 (includes corresponding Graph/Chart).......182

Table 93: Number of Organ Transplants (Excluding Cornea) in Pediatric Patients in South Africa by Organ for Years 2008 & 2009 (includes corresponding Graph/Chart).......182
1$350
   Table 94: Number of Heart Transplants in South Africa for Years 2005 through 2009 (includes corresponding Graph/Chart).......183

Table 95: Number of Kidney Transplants in South Africa for Years 2005 through 2009 (includes corresponding Graph/Chart).......183

Table 96: Number of Lung Transplants in South Africa for Years 2005 through 2009 (includes corresponding Graph/Chart).......183
1$350
   Table 97: Organ Transplants (Excluding Cornea) in South Africa by Region (2008 & 2009): Percentage Breakdown of Volume Procedures for Cape Town, Johannesburg, Durban, Pretoria and Bloemfontein (includes corresponding Graph/Chart).......184

Table 98: Cornea Transplants in South Africa by Region (2008 & 2009): Percentage Breakdown of Volume Procedures for Johannesburg, Durban, Cape Town, Pretoria and Port Elizabeth (includes corresponding Graph/Chart).......184
1$350
   B. Market Analytics.......185
Table 99: Rest of World Recent Past, Current & Future Market Analysis for Organ Transplantation by Organ Type – Heart, Kidney, Liver, Pancreas and Lung Independently Analyzed by Number of Procedures for Years 2009 through 2015 (includes corresponding Graph/Chart).......185
1$350
   Table 100: Rest of World Historic Review for Organ Transplantation by Organ Type – Heart, Kidney, Liver, Pancreas and Lung Independently Analyzed by Number of Procedures for Years 2003 through 2008 (includes corresponding Graph/Chart).......1861$350
   Table 101: Rest of World 11-Year Perspective for Organ Transplantation by Organ Type – Percentage Breakdown of Number of Procedures for Heart, Kidney, Liver, Pancreas and Lung Markets for Years 2005, 2010 & 2015 (includes corresponding Graph/Chart).......1871$350
COMPETITION 225$995
  
Total Companies Profiled: 77 (including Divisions/Subsidiaries - 90)

Region/Country                 Players


The United States                 60    
Canada                             2
Japan                             10 
Europe                            16 
     France                        1
     Germany                       6
     The United Kingdom            2
     Italy                         3
Asia-Pacific (Excluding Japan)     1
Middle East                        1
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