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PROTEOMICS - A GLOBAL STRATEGIC BUSINESS REPORT   

Research Abstract

This report analyzes the worldwide markets for Proteomics in US$ Million by the following product segments: Expression Proteomics, Functional Proteomics, and Structural Proteomics.The report provides separate comprehensive analytics for the US, Canada, Japan, Europe, and Rest of World. Annual estimates and forecasts are provided for each region for the period of 2009 through 2015. Also, a six-year historic analysis is provided for these markets. The report profiles 168 companies including many key and niche players such as ActivX Biosciences, Inc., Adnexus Therapeutics, Agilent Technologies, Inc., Bio-Rad Laboratories, Inc., Bruker Daltonics, Inc., Caliper Life Sciences, Caprion Proteomics, Inc., Digilab Genomic Solutions, Inc., Dionex Corporation, GE Healthcare, Biacore Life Sciences, Geneva Bioinformatics S.A., Human Genome Sciences, Inc., Hybrigenics SA, Life Technologies Corporation, Millipore Corp., PerkinElmer, Inc., Shimadzu Biotech, Sigma-Aldrich Corporation, Thermo Fisher Scientific, Tyrian Diagnostics Ltd., Waters Corp., Xencor Inc., and Zyomyx, Inc. Market data and analytics are derived from primary and secondary research. Company profiles are mostly extracted from URL research and reported select online sources.

Code : MCP-1029
Price : $4500
Companies : 168
Pages : 694
Date : September 2010
Market Data Tables : 18

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 TABLE OF CONTENTS

  PROTEOMICS (Complete Report) Pages : 694   | $4500
 
  1. INTRODUCTION, METHODOLOGY & PRODUCT DEFINITIONS.......14 $100  
   Study Reliability and Reporting Limitations.......1  
   Disclaimers.......2  
   Data Interpretation & Reporting Level.......3
Quantitative Techniques & Analytics.......3
Product Definitions and Scope of Study.......3
  
   Expression Proteomics.......4
Functional Proteomics.......4
Structural Proteomics.......4
  
  2. GLOBAL MARKET OVERVIEW........59 $650  
   Proteomics – The Current Spotlight........5
Market Drivers........5
Transition from Genomics to Proteomics........5
1$100
   Industrialization of Proteomics Research........6
International Initiatives Light-up Proteomics Market........6
Factors Limiting Market Growth........6
Recession and the Life Sciences Industry........6
1$100
   Biotechnology Sector – Affected by Collapse of Capital Market........71$100
   Tough Times for Market Participants........8
Proteomics Technologies: Growing in Significance........8
1$100
   Transformation of Drug Discovery through Proteomics and Genomics........9
Proteomics: A Critical Drug Discovery Tool........9
2$200
   Global Proteomics Sample Preparation Market - On a Growth Curve........11
Challenges Facing Proteomics Sample Preparation Market........11
Challenges Facing Proteomics Industry........11
Protein Chemistry and its Complexities........11
1$100
   Integration of Data & Equipment........12
Data Validation - A Burning Issue........12
Standardization & Consistency - A Prime Concern........12
Incomplete and Disorganized Data........12
2$200
  3. INDUSTRY COMPETITION........143 $300  
   Industry Participants........14
Proteomics Market Worldwide: Competitive Landscape........14
Proteomics Supplier Market........14
1$100
   Tool Providers: Leading the Proteomics Market........15
Applied Biosystems-Invitrogenc Corporation Merger – A Key Development........15
1$100
   Challenges Ahead........16
Designing a Novel Business Model........16
1$100
  4. PRODUCT AND TECHNOLOGY OVERVIEW........178 $600  
   Proteins, Proteome and Proteomics!!! - What are They?........17
Proteomics – An Introduction........17
1$100
   Genesis of Proteomics........18
Tales From Times Gone By........18
Components of Proteomics........18
Expression Proteomics........18
1$100
   Functional Proteomics........19
Cell-map Proteomics........19
Structural Proteomics........19
Technologies and Proteomics........19
1$100
   Proteomics and Genomics........20
Proteomics and Genomics: A Comparison........20
Protein Production Pathway: From Gene Expression to Functional Protein with
  Controls........20
1$100
   From Genomics to Proteomics........21
Functional Genomics and Proteomics........21
1$100
   Push From Genomic Information........22
Standard Proteomics Approach........22
1$100
   Sample Preparation - Step I........23
Protein Separation - Step II........23
Protein Visualization........23
Protein Expression Analysis-Step III........23
1$100
   Protein Identification - Step IV........24
Data Storage and Processing - Step V........24
1$100
  5. OVERVIEW OF PROTEOMICS TECHNOLOGIES........2512 $850  
   A Snapshot of Various Proteomics Tools........25
An Insight into Various Proteomics Technologies and their Application Areas........25
Protein Separation........25
1$100
   2-Dimensional Gel Electrophoresis (2DGE)........261$100
   Protein Characterization........27
Analysis of Protein Through Mass Spectrometry........27
1$100
   MS and Proteins........282$200
   Y2H, Yeast 2-Hybrid System........301$100
   Protein Microarrays........31
Chip Technology........31
Microfluidic Applications........31
1$100
   Role of Bioinformatics in Proteomics........32
Bioinformatics Applications and Tools in Proteomics........32
2$200
   Emerging Proteomics Technologies........34
MudPIT........34
ICAT ........34
Phage Display Technique........34
1$100
   Advanced Proteomics Technologies: Structural Analysis Tools........35
X-ray Crystallography........35
Nuclear Magnetic Resonance (NMR)........35
In silico Modelling........35
1$100
   Physicochemical Factors Constraining Metabolic Functions........36
1$100
  6. END-USE APPLICATION AREAS........374 $300  
   End-Use Application Areas........371$100
   Proteomics in Drug and Diagnostic Discovery........38
Proteomics and Drug Discovery........38
1$100
   Proteomic Approaches Gain Prominence in Cancer Drug Discovery........39
2$200
  7. NEW PRODUCT SOLUTIONS/DEVELOPMENTS........414 $300  
   Gentel Biosciences Launches Proteomics Multi-System........41
Arrayit Discovers New Proteomic Biomarkers........41
Kinexus Bioinformatics Launches Peptide Development Facility........41
1$100
   Bruker Daltonics Unveils ultrafleXtreme™ MALDI- TOF/TOF Mass Spectrometer........421$100
   Agilent Technologies Rolls Out HPLC-Chip........43
Applied Biosystems and MDS Introduce AB SCIEX TOF/TOF™ 5800 System........43
Applied Biomics Extends Proteomics Service Offerings........43
1$100
   AnaSpec Introduces Keratin Antibodies........44
caprotec bioanalytics Unveils cAMP caproKit and SAH caproKit........44
Huzhou Sai'erdi Biopharmaceutical Introduces Proteomic Fingerprint Technology Test
  Kit........44
1$100
  8. PRODUCT INTRODUCTIONS/INNOVATIONS IN RECENT PAST – A PERSPECTIVE BUILDER........4514 $950  
   Agilent Technologies Launches Complex Proteomics Standard........45
MDS Analytical Technologies Launches Three New Instruments........45
Protea Biosciences Unveils gelSTAT........45
1$100
   Sage-N Research and Thermo Fisher Introduce SORCERER Enterprise Software........46
Thermo Fisher Unveils Proteomics Workflow Solution........46
Promega and GeneCopoeia Launch OmicsLink ORF Expression Clones........46
1$100
   Applied Biosystems and MDS Analytical Technologies Launch Integrated Mass Spectrometry
  Solutions........47
1$100
   Dionex Launches UltiMate® 3000 Proteomics MDLC System........48
Millipore Unveils SNAP i.d.™ Protein Detection System........48
Thermo Fisher Launches Mass Spectrometry Technologies........48
1$100
   Waters Unveils Novel Column Chemistries........49
Waters Corporation Introduces Waters® SYNAPT™ MS System........49
1$100
   Bruker Daltonics Introduces Advanced ETD II Module........50
Applied Biosystems Expands its iTRAQ® Line of Labeling Reagents........50
PerkinElmer Expands Imaging Technologies and Protein Analysis Product
  Portfolio........50
1$100
   Sigma-Aldrich Introduces new Proteomics Dynamic Range Standard........51
Thermo Fisher Scientific Expands Mass Spectrometry Portfolio........51
Bruker Daltonics Launches New Versions of Compass™ and ProteinScape™ Softwares........51
1$100
   Applied Biosystems and Sciex Roll Out New Proteomic Tools........52
Bruker Daltonics Rolls Out New Compass™ 1.2 Software........52
Bruker Daltonics Unveils New Mass Spectrometer, apex®-ultra FTMS........52
1$100
   Thermo Fisher Unveils the Latest LTQ XL mass spectrometer........53
Genedata Introduces Genedata Expressionist® Pro 3.0........53
Biozentrum to Employ GeneBio’s Phenyx as Primary Search Engine........53
1$100
   Shimadzu Biotech Unveils AXIMA-TOF2........54
Waters Corporation Unveils Latest Columns for Peptide Analysis and Isolation........54
1$100
   Applied Biosystems and MDS Sciex Unveil QSTAR® Elite LC/MS/MS System........55
Waters Corporation to Roll out Updated ProteinLynx Global SERVER™ Version........55
Syngene Unveils the Latest Integrated Proteomics Products........55
1$100
   Sigma Unveils the Latest ProteoPrep 20 Plasma Immunodepletion Kit........56
Sigma-Aldrich Introduces First Commercial Proteomics Standard........56
Bruker Daltonics and Serva Electrophoresis Unveil ICPL Triplex kit........56
1$100
   Agilent Unveils 3100 OFFGEL Fractionator........57
Agilent Technologies Unveils Multiple Affinity Removal System 7........57
Bio-Rad Unveils Proteon XPR36 Protein Interaction Array System........57
1$100
   Sigma-Aldrich Adds Panorama Human Kinase v1 Array to Extend Panorama Protein Array
  Line........58
PerkinElmer Expands Proteomic Research Tools Offering........58
Waters Launches Advanced Version of Proteomics Research Software........58
Lumera to Develop New Protein Biochip in Collaboration with HMS........58
1$100
  9. RECENT INDUSTRY ACTIVITY........599 $700  
   Thermo Fisher Scientific Takes Over Proxeon........59
TriLink BioTechnologies and Nacalai USA Sign Distribution Agreement........59
Cell Biosciences to Take Over Alpha Innotech........59
1$100
   Eurogentec to Take Over Ana Spec........60
Merck Takes Over Bangalore Genei........60
Cell Biosciences Takes Over Protein Forest........60
1$100
   Microsoft to Acquire Rosetta Bio Software Assets........61
CCMB and Bio-Rad India Sign MoU........61
SAIC-Frederick and Sensor Technologies Ink Collaboration Agreement........61
1$100
   NuSep Signs Purchase Agreement with BioInquire........62
Intrinsic Bioprobes Bags Contract from NCI........62
HORIBA Jobin Yvon Acquires GenOptics........62
Gentel Biosciences Partners with Eprogen........62
1$100
   Bruker Daltonics Installs High-Field 15 Tesla and 12 Tesla FTMS Systems at
  LUMC........63
1$100
   Genedata Extends Collaboration with Roche........64
AliX Merges with Novalyst Discovery to form NovAliX........64
BioPike and AnaSpec Sign Agreement........64
1$100
   Sigma-Aldrich Purchases Electrophoresis Business of NextGen Sciences........65
Fujifilm Purchases Additional Stake in Perseus Proteomics........65
1$100
   Sigma-Aldrich Buys Seppro® Depletion Technology and 700 Antibodies........66
Oxford Gene Technology Purchases Sense Proteomic........66
Center for Cancer Research Acquires Waters® UPLC/MS Systems........66
2$200
  10. CORPORATE ACTIVITY IN RECENT PAST – A PERSPECTIVE BUILDER........6815 $1000  
   Invitrogen Merges with Applied Biosystems........68
Enzo Biochem Purchases BIOMOL International........68
AnaSpec Inks Agreement with Yope Biotechnology........68
1$100
   Covance Acquires Interest in Caprion Proteomics........69
Institute of Biotechnology and Chemical Engineering Department of University of
  Cambridge Merge........69
Thermo Fisher Scientific Purchases Affinity BioReagents........69
Thermo Fisher Scientific Snaps Up Open Biosystems........69
1$100
   Sense Proteomic Spins Off to Become a Biomarker Discovery Entity........70
Affymetrix Purchases USB........70
Malvern Instruments Purchases Viscotek........70
Geneva Bioinformatics Signs Agreement with Proxeon........70
1$100
   Thermo Fisher Scientific Inks Agreement with KPL........71
Caprotec Bioanalytics and Merck Sign Agreement........71
Lumera to Close Plexera........71
1$100
   Waypoint Biosystems and University of Texas M. D. Anderson Cancer Center Sign
  Agreement........72
Thermo Fisher Scientific and Vascular Proteomics Group Enter into Partnership........72
Sigma-Aldrich Partners with Atlas Antibodies........72
1$100
   Geneva Bioinformatics Inks Agreement with Chinese State Key Laboratory of
  Proteomics........73
Cels Establishes New Proteomics Unit........73
Genencor Signs Agreement with Coda Genomics........73
Fluorotechnics to Purchase The Gel Company........73
1$100
   Calibrant Biosystems and Armed Forces Institute of Pathology Sign Agreement........74
Thermo Fisher Incorporates Proteome Discoverer by InforSense in its Products........74
BRIMS Partners with CAPMM........74
1$100
   Proteome Systems Enters into Licensing Agreement with Agilent Technologies........75
Vanderbilt University Medical Center Enters into Collaboration with Waters........75
1$100
   Sigma-Aldrich Enters Exclusive Alliance with Atlas Antibodies to Distribute Prestige
  Antibodies™........76
Nonlinear Dynamics Inks Distribution Agreement with UVP, LLC........76
Plexera Enters into Access Agreement with Auguron for NAPPA........76
1$100
   NextGen and Paragon Bioservices Enter into a Commercial Partnership Agreement........77
Arrayit Deploys Advanced Proteomics Platform........77
Proteome Software Enters into Collaboration with Waters Corporation........77
Shimadzu and Fred Hutchinson Cancer Research Center Collaborate........77
1$100
   Digilab Acquires Genomic Solutions and MAIA Scientific from Harvard Bioscience........78
Power3 Ropes in FAH to Distribute its BC-SeraPro™ in the Middle East........78
Thallion Sells Majority Stake to US-based Private Equity Firm, Great Point
  Partners........78
Ecopia and Caprion Merge to Form Thallion Pharmaceuticals........78
1$100
   BG Medicine and Applied Biosystems Collaborate for Biomarker Discovery and
  Development........79
Bio-Rad Acquires Ciphergen’s Proteomics Instrument Business........79
BioMachines Establishes New Proteomics Services Unit........79
1$100
   GE Acquires Biacore........80
Fuji Film Acquires Minority Stake in Perseus........80
Cenix BioScience, Applied Biosystems, and Biotec of the Technische Universität Dresden
  Collaborate........80
1$100
   GeneBio and Goodlett Enter into Collaboration........81
Genetix Group Acquires Applied Imaging........81
Massively Parallel Technologies Signs Deal with University of Colorado........81
1$100
   Genospectra Plans Merger with Panomics........82
PerkinElmer Announces Acquisition of Proteomics Labeling Technology ........82
ActivX Biosciences Extends Alliance with Pfizer........82
1$100
  11. FOCUS ON SELECT KEY PLAYERS........838 $600  
   ActivX Biosciences, Inc. (USA)........83
Adnexus Therapeutics (USA)........83
Agilent Technologies, Inc. (USA)........83
1$100
   Bio-Rad Laboratories, Inc.........84
Bruker Daltonics, Inc. (USA)........84
Caliper Life Sciences (US)........84
1$100
   Caprion Proteomics, Inc. (Canada)........85
Digilab Genomic Solutions, Inc. (US)........85
Dionex Corporation (USA)........85
1$100
   GE Healthcare (United Kingdom)........86
Biacore Life Sciences........86
Geneva Bioinformatics S.A. (Switzerland)........86
Human Genome Sciences, Inc. (USA)........86
1$100
   Hybrigenics SA (France)........87
Life Technologies Corporation (USA)........87
Millipore Corp. (USA)........87
1$100
   PerkinElmer, Inc. (USA)........88
Shimadzu Biotech (Japan)........88
Sigma-Aldrich Corporation (USA)........88
1$100
   Thermo Fisher Scientific (USA)........89
Tyrian Diagnostics Ltd. (Australia)........89
Waters Corp. (USA)........89
1$100
   Xencor Inc. (USA)........90
Zyomyx, Inc. (USA)........90
1$100
  12. GLOBAL MARKET PERSPECTIVE........91   
   Table 1: World Recent Past, Current & Future Analysis for Proteomics by Geographic Region – US, Canada, Japan, Europe and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2009 through 2015 (includes corresponding Graph/Chart)........911$350
   Table 2: World Historic Review for Proteomics by Geographic Region – US, Canada, Japan, Europe and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2003 through 2008 (includes corresponding Graph/Chart)........921$350
   Table 3: World 11-Year Perspective for Proteomics by Geographic Region – Percentage Breakdown of Dollar Sales for US, Canada, Japan, Europe and Rest of World Markets for Years 2005, 2010 and 2015 (includes corresponding Graph/Chart)........931$350
   Table 4: World Recent Past, Current & Future Analysis for Proteomics by Segment – Expression Proteomics, Functional Proteomics and Structural Proteomics Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2009 through 2015 (includes corresponding Graph/Chart)........941$350
   Table 5: World Historic Review for Proteomics by Segment – Expression Proteomics, Functional Proteomics and Structural Proteomics Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2003 through 2008 (includes corresponding Graph/Chart)........951$350
   Table 6: World 11-Year Perspective for Proteomics by Segment – Percentage Breakdown of Dollar Sales for Expression Proteomics, Functional Proteomics and Structural Proteomics Markets for Years 2005, 2010 and 2015 (includes corresponding Graph/Chart)........96
1$350
  13. GLOSSARY OF TERMS........973 $300  
   1-D, 2-D, 3-D........97
Atmospheric Pressure Ionisation........97
Electrophoresis........97
Functional Genomics........97
High-Throughput........97
Liquid Chromatography (LC)........97
Mass Spectrometry (MS)........97
1$100
   Matrix-Assisted Laser Desorption Ionisation (MALDI)........98
Nuclear Magnetic Resonance........98
X-ray Diffraction........98
Yeast Two-Hybrid System........98
2D-PAGE (Two-dimensional PolyAcrylamide Gel Electrophoresis)........98
TOF (Time of Flight)........98
Quadrupole........98
Q-TOF (Quadrupole Time of Flight)........98
1$100
   ESI (Electrospray Ionisation)........99
1$100
  14. THE UNITED STATES........1002 $350  
   A. Market Analysis........100
Outlook........100
Proteomics Sample Preparation Market........100
1$100
   B. Market Analytics........101
Table 7: US Recent Past, Current & Future Analysis for Proteomics Market Analyzed with Annual Sales Figures in US$ Million for Years 2009 through 2015 (includes corresponding Graph/Chart)........101

Table 8: US Historic Review for Proteomics Market Analyzed with Annual Sales Figures in US$ Million for Years 2003 through 2008 (includes corresponding Graph/Chart)........101
1$350
  15. CANADA........1022 $350  
   A. Market Analysis........102
Outlook........102
1$100
   B. Market Analytics........103
Table 9: Canadian Recent Past, Current & Future Analysis for Proteomics Market Analyzed with Annual Sales Figures in US$ Million for Years 2009 through 2015 (includes corresponding Graph/Chart)........103

Table 10: Canadian Historic Review for Proteomics Market Analyzed with Annual Sales Figures in US$ Million for Years 2003 through 2008 (includes corresponding Graph/Chart)........103
1$350
  16. JAPAN........1042 $575  
   Market Analysis........104
Table 11: Japanese Recent Past, Current & Future Analysis for Proteomics Market Analyzed with Annual Sales Figures in US$ Million for Years 2009 through 2015 (includes corresponding Graph/Chart)........104
1$350
   Table 12: Japanese Historic Review for Proteomics Market Analyzed with Annual Sales Figures in US$ Million for Years 2003 through 2008 (includes corresponding Graph/Chart)........105
1$350
  17. EUROPE........1068 $1400  
   A. Market Analysis........106
Outlook........106
Proteomics Research in Europe – An Overview........106
1$100
   Table 13: European Proteomics Market (2009E): Percentage Breakdown of Deployment of Proteomics Technologies in End-Use Segments - Research and Academic Institutions, Pharmaceutical Companies and Clinical Laboratories (includes corresponding Graph/Chart)........107
Protein Identification Market........107
1$350
   Protein Separation Market........108
Market Challenges........108
Gaining Edge in the Proteomics Industry – Player Strategies........108
1$100
   European 2DE Market – Benefiting from Recession........109
Review of Select Markets........109
Germany........109
1$100
   The United Kingdom........1101$100
   B. Market Analytics........111
Table 14: European Recent Past, Current & Future Analysis for Proteomics by Geographic Region – France, Germany, UK and Rest of Europe Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2009 through 2015 (includes corresponding Graph/Chart)........111
1$350
   Table 15: European Historic Review for Proteomics by Geographic Region – France, Germany, UK and Rest of Europe Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2003 through 2008 (includes corresponding Graph/Chart)........1121$350
   Table 16: European 11-Year Perspective for Proteomics by Geographic Region – Percentage Breakdown of Dollar Sales for France, Germany, UK and Rest of Europe Markets for Years 2005, 2010 and 2015 (includes corresponding Graph/Chart)........113
1$350
  18. REST OF WORLD........1143 $700  
   A. Market Analysis........114
Outlook........114
Australia........114
India........114
Indian Scientific Research towards Functional Genomics and Proteomics........114
1$100
   B. Market Analytics........115
Table 17: Rest of World Recent Past, Current & Future Analysis for Proteomics Market Analyzed with Annual Sales Figures in US$ Million for Years 2009 through 2015 (includes corresponding Graph/Chart)........115
1$350
   Table 18: Rest of World Historic Review for Proteomics Market Analyzed with Annual Sales Figures in US$ Million for Years 2003 through 2008 (includes corresponding Graph/Chart)........1161$350
COMPETITION 571$995
  
Total Companies Profiled: 168 (including Divisions/Subsidiaries - 181)

Region/Country                 Players


The United States                101   
Canada                            10
Japan                              6
Europe                            59
     France                        5
     Germany                      17
     The United Kingdom           19
     Rest of Europe               18
Asia-Pacific (Excluding Japan)     3
Middle East                        2
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