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GENE AMPLIFICATION TECHNOLOGIES - A GLOBAL STRATEGIC BUSINESS REPORT   

Research Abstract

This report analyzes the worldwide markets for Gene Amplification Technologies in US$ Million by the following Product segments: Polymerase Chain Reaction, and Other Gene Amplification Technologies. The report provides separate comprehensive analytics for the US, Canada, Japan, Europe, and Rest of World. Annual estimates and forecasts are provided for the period 2009 through 2017. Also, a six-year historic analysis is provided for these markets. Market data and analytics are derived from primary and secondary research. Company profiles are primarily based upon search engine sources in the public domain. The report profiles 90 companies including many key and niche players such as -

Abbott Laboratories
Becton, Dickinson and Company
bioMerieux
Bio-Rad Laboratories
Cepheid
Life Technologies Corp.

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Code: MCP-1102
Price: $4500
Companies: 90
Pages: 500
Date: February 2012
Market Data Tables: 43
 


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TABLE OF CONTENTS


  GENE AMPLIFICATION TECHNOLOGIES (Complete Report) Pages : 500   | $4500

I. INTRODUCTION, METHODOLOGY & PRODUCT DEFINITIONS  
   Study Reliability and Reporting Limitations.....I-1  
   Disclaimers.....I-2
Data Interpretation & Reporting Level.....I-2
  
   Quantitative Techniques & Analytics.....I-3
Product Definitions and Scope of Study.....I-3
Definitions.....I-3
Polymerase Chain Reaction.....I-3
Other Gene Amplification Technologies.....I-3
  
II. EXECUTIVE SUMMARY44$2350
  1. INDUSTRY OVERVIEW.....II-12 $200  
   PCR Dominates Amplification Technologies.....II-1
Growth Prospects Live in PCR Market despite Competition.....II-1
Miniaturization – The Next Big Focus.....II-1
1$100
   Critical in Diagnostic Procedures.....II-2
Leading Players.....II-2
1$100
  2. TECHNOLOGY OVERVIEW.....II-37 $495  
   Definition of Gene Amplification.....II-3
Target vs. Signal Amplification.....II-3
Available Types of Gene Amplification Technologies.....II-3
Polymerase Chain Reaction.....II-3
1$100
   Reagents and Equipment required for PCR.....II-4
Reaction Steps.....II-4
Denaturation.....II-4
Annealing.....II-4
Extension.....II-4
1$100
   Detection of Amplified Product/DNA.....II-5
(Q&Q) PCR.....II-5
Reverse Transcriptase PCR (RT-PCR).....II-5
1$100
   Alternative Technologies to PCR.....II-6
OmniPlex.....II-6
Strand Displacement Amplification.....II-6
1$100
   Ligase Chain Reaction.....II-7
LCR Involves a Cyclic Two-Step Reaction.....II-7
Gene Amplification Technology (GAT).....II-7
Hybrid Capture.....II-7
Isothermal DNA Amplification Techniques.....II-7
Rolling circle Amplification in Diagnostics.....II-7
1$100
   Ican Isothermal Gene Amplification Technology.....II-8
BioHelix HDA Technology.....II-8
Other Amplification Technologies.....II-8
Signal Amplification Technology.....II-8
Transcription Mediated Amplification.....II-8
1$100
   DNA cleavage-based signal amplification.....II-9
Ramification Amplification Method.....II-9
1$100
  3. END-USE MARKET ANALYSIS.....II-104 $295  
   Medical and Diagnostics.....II-10
Role of Amplification Technology in the Diagnoses of Infectious Diseases.....II-10
Diagnosis of Infectious Diseases by PCR.....II-10
1$100
   Detection of Antimicrobial Resistance.....II-11
PCR Based Nucleic Acid Amplification for Detection of Antimicrobial Agents.....II-11
Nucleic Acid Amplification Testing (NAT).....II-11
1$100
   Nucleic Acid Amplification Methods.....II-12
DNA Amplification Technology in the Diagnosis of Infectious Diseases.....II-12
Forensic and Paternity Testing.....II-12
1$100
   Food Safety.....II-131$100
  4. PRODUCT INNOVATIONS/LAUNCHES.....II-143 $295  
   DuPont Qualicon Launches New BAX® System Real-Time PCR Assay.....II-14
Rubicon Genomics Launches PicoPlex Single Cell WGA Kit.....II-14
NuGEN Unveils WT-OvationTM RNA Amplification System for Whole-Transcriptome Gene
  Expression Analysis.....II-14
1$100
   DuPont Qualicon Obtains Approval from Russian Federal Consumer Rights Protection and
  Human Health Control Service for BAX™ System.....II-15
DuPont Qualicon Receives Approval from the General Administration of Quality
  Supervision, Inspection and Quarantine for BAX® system.....II-15
1$100
   Seegene Enters into Partnership with Shimadzu.....II-16
Bio-Rad Launches New CFX96 PCR Detection System.....II-16
1$100
  5. PRODUCT INNOVATIONS/LAUNCHES IN RECENT PAST – A PERSPECTIVE BUILDER.....II-175 $395  
   Roche Introduces Genome Sequencer FLX System.....II-17
QIAGEN Launches TopTaq DNA Polymerase.....II-17
Applied Biosystems Introduces TaqMan Array Human MicroRNA Panel.....II-17
1$100
   Spartan Introduces Spartan DX.....II-18
Applied Biosystems Launches Forensic Tools.....II-18
Applied Biosystems Introduces StepOne Real-Time PCR System.....II-18
1$100
   Sigma-Aldrich Unveils GenomePlex Tissue Whole Genome Amplification Kit.....II-19
QIAGEN Rolls Out Wide RNAi and SYBR® Green-based RT- PCR.....II-19
Applied Biosystems Launches 7500 Fast Real-Time PCR System.....II-19
Applied Biosystems Launches 9800 Fast PCR System.....II-19
1$100
   7900HT Fast Real-Time PCR System from Applied Biosystems.....II-20
Enzo Life Sciences Introduces New Advanced Amplification Technology.....II-20
Applied Biosystems Unveils AmpFSTR® Yfiler™ PCR Amplification Kit.....II-20
Amersham Launches GenomiPhi.....II-20
1$100
   Rubicon Genomics Launches GenomePlex WGA.....II-21
Agilent Introduces Amplification Kit.....II-21
Linden Introduces Snapshot mRNA.....II-21
Rubicon Launches OmniPlex™.....II-21
1$100
  6. RECENT INDUSTRY ACTIVITY.....II-225 $395  
   QIAGEN Acquires Rights to 70 Molecular Food Safety Tests from ifp.....II-22
Life Technologies to Acquire Geneart.....II-22
Thermo Fisher Scientific Takes Over Finnzymes.....II-22
Abbott Inks Agreement with GlaxoSmithKline for Developing Molecular Diagnostic
  Test.....II-22
1$100
   DXS Purchases License for P13K Gene from Johns Hopkins University.....II-23
Qiagen Acquires SABiosciences.....II-23
DuPont Qualicon Obtains License from DxS for Scorpions® Technology.....II-23
BD Takes Over HandyLab.....II-23
1$100
   Life Technologies Takes Over BioTrove.....II-24
Merck Merges with Schering-Plough.....II-24
QIAGEN Acquires Licenses from Idaho Technology and Roche.....II-24
1$100
   Response Genetics Inks Non-Exclusive Agreement with Roche Diagnostics.....II-25
Invitrogen Announces Merger with Applied Biosystems.....II-25
Hologic Acquires Third Wave Technologies.....II-25
BIOTECON Acquires Roche's Technology License.....II-25
QIAGEN Signs a Global Licensing Agreement with BioHelix.....II-25
1$100
   BioTrove and Gene Express Receive NIH Grant for Innovative Bio-experimentation.....II-261$100
  7. CORPORATE ACTIVITY IN THE RECENT PAST – A PERSPECTIVE BUILDER.....II-275 $395  
   SuperArray Bioscience Inks License Agreement with Applied Biosystems.....II-27
Merck Capital Takes Over Minority Interest in High Throughput Genomics.....II-27
NuGEN Enters into a Service Agreement with ExonHit.....II-27
Qiagen Enters into License Agreements with Roche and Ortho-Clinical.....II-27
1$100
   Agilent Takes Over Stratagene.....II-28
Eiken Chemical Inks Licensing Agreement with Meridian Bioscience.....II-28
Sigma-Aldrich Acquires JRH.....II-28
1$100
   Sigma-Aldrich Snaps Up Proligo.....II-29
Beckman Acquires Agencourt.....II-29
Roche Diagnostics and Applera Corporation Expand PCR Licensing Program.....II-29
Mount and Hamilton Receive Patent.....II-29
Invitrogen Bags License from Applied Biosystems.....II-29
OriGene to Access TrueClone.....II-29
Orchid BioSciences to Turn into Orchid Cellmark.....II-29
1$100
   QIAGEN Purchases Assets of Molecular Staging.....II-30
Cepheid, Applied Biosystems and Celera Diagnostics Sign Patent License
  Agreement.....II-30
Abbott Enters into Agreement with BioGenex.....II-30
Roche Inks Licensing Agreement with Incyte Corp.....II-30
1$100
   Rubicon Genomics Signs Licensing Agreement with Sigma-Aldrich.....II-31
BioMérieux Teams-up with Cepheid.....II-31
Molecular Staging Collaborates with Eli Lilly.....II-31
Pacific Biometrics Inc. Receives Gene Amplification Patent.....II-31
Rubicon Introduces Service for Genome Amplification.....II-31
Takara Obtains Patent for New Amplification Method.....II-31
1$100
  8. FOCUS ON SELECT GLOBAL PLAYERS.....II-324 $295  
   Abbott Laboratories (US).....II-32
Becton, Dickinson and Company (US).....II-32
bioMérieux (France).....II-32
1$100
   Bio-Rad Laboratories (US).....II-33
Cepheid (US).....II-33
Life Technologies Corp. (US).....II-33
1$100
   QIAGEN N.V. (The Netherlands).....II-34
Roche Diagnostics (Switzerland).....II-34
Rubicon Genomics (US).....II-34
1$100
   Takara Bio, Inc......II-351$100
  9. GLOBAL MARKET PERSPECTIVE.....II-36   
   Table 1: World Recent Past, Current & Future Market Analysis for Gene Amplification Technologies by Geographic Region – US, Canada, Japan, Europe, and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2009 through 2017 (includes corresponding Graph/Chart).....II-361$350
   Table 2: World Historic Review for Gene Amplification Technologies by Geographic Region – US, Canada, Japan, Europe, and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2003 through 2008 (includes corresponding Graph/Chart).....II-371$350
   Table 3: World 15-Year Perspective for Gene Amplification Technologies by Geographic Region – Percentage Breakdown of Dollar Sales for US, Canada, Japan, Europe, and Rest of World Markets for Years 2003, 2011 & 2017 (includes corresponding Graph/Chart).....II-381$350
   Table 4: World Recent Past, Current & Future Market Analysis for Polymerase Chain Reaction (PCR) by Geographic Region – US, Canada, Japan, Europe, and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2009 through 2017 (includes corresponding Graph/Chart).....II-391$350
   Table 5: World Historic Review for Polymerase Chain Reaction (PCR) by Geographic Region – US, Canada, Japan, Europe, and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2003 through 2008 (includes corresponding Graph/Chart).....II-401$350
   Table 6: World 15-Year Perspective for Polymerase Chain Reaction (PCR) by Geographic Region – Percentage Breakdown of Dollar Sales for US, Canada, Japan, Europe, and Rest of World Markets for Years 2003, 2011 & 2017 (includes corresponding Graph/Chart).....II-411$350
   Table 7: World Recent Past, Current & Future Market Analysis for Other Gene Amplification Technologies by Geographic Region – US, Canada, Japan, Europe, and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2009 through 2017 (includes corresponding Graph/Chart).....II-421$350
   Table 8: World Historic Review for Other Gene Amplification Technologies by Geographic Region – US, Canada, Japan, Europe, and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2003 through 2008 (includes corresponding Graph/Chart).....II-431$350
   Table 9: World 15-Year Perspective for Other Gene Amplification Technologies by Geographic Region – Percentage Breakdown of Dollar Sales for US, Canada, Japan, Europe, and Rest of World Markets for Years 2003, 2011 & 2017(includes corresponding Graph/Chart).....II-441$350
III. MARKET35$2150
  1. THE UNITED STATES.....III-15 $595  
   A. Market Analysis.....III-1
Real-Time PCR Market in North America: A Primer.....III-1
Table 10: Leading Suppliers of Individual qPCR Reagents in North America (2008): Percentage Dollar Share Breakdown of Invitrogen, Applied Biosystems, Roche Applied, Bio-Rad/ MJ, BD Clontech, Promega, Amblon, NEB, Qiagen, and Others (includes corresponding Graph/Chart).....III-1
1$200
   Key Factors (Ranked in Order) in Selection of Real-Time/qPCR Platforms
  Manufacturers.....III-2
Top 10 Research Applications of Real-Time Quantitative PCR (qPCR) in North
  America.....III-2
1$75
   B. Market Analytics.....III-3
Table 11: US Recent Past, Current & Future Analysis for Gene Amplification Technologies by Segment – Polymerase Chain Reaction (PCR) and Other Gene Amplification Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2009 through 2017 (includes corresponding Graph/Chart).....III-3
1$200
   Table 12: US Historic Review for Gene Amplification Technologies by Segment – Polymerase Chain Reaction (PCR) and Other Gene Amplification Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2003 through 2008 (includes corresponding Graph/Chart).....III-41$200
   Table 13: US 15-Year Perspective for Gene Amplification Technologies by Segment – Percentage Breakdown of Dollar Sales for Polymerase Chain Reaction (PCR) and Other Gene Amplification Markets for Years 2003, 2011 & 2017 (includes corresponding Graph/Chart).....III-51$200
  2. CANADA.....III-63 $495  
   Market Analysis.....III-6
Table 14: Canadian Recent Past, Current & Future Analysis for Gene Amplification Technologies by Segment – Polymerase Chain Reaction (PCR) and Other Gene Amplification Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2009 through 2017 (includes corresponding Graph/Chart).....III-6
1$200
   Table 15: Canadian Historic Review for Gene Amplification Technologies by Segment – Polymerase Chain Reaction (PCR) and Other Gene Amplification Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2003 through 2008 (includes corresponding Graph/Chart).....III-71$200
   Table 16: Canadian 15-Year Perspective for Gene Amplification Technologies by Segment – Percentage Breakdown of Dollar Sales for Polymerase Chain Reaction (PCR) and Other Gene Amplification Markets for Years 2003, 2011 & 2017 (includes corresponding Graph/Chart).....III-81$200
  3. JAPAN.....III-93 $495  
   Market Analysis.....III-9
Table 17: Japanese Recent Past, Current & Future nalysis for Gene Amplification Technologies by Segment – Polymerase Chain Reaction (PCR) and Other Gene Amplification Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2009 through 2017 (includes corresponding Graph/Chart).....III-9
1$200
   Table 18: Japanese Historic Review for Gene Amplification Technologies by Segment – Polymerase Chain Reaction (PCR) and Other Gene Amplification Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2003 through 2008 (includes corresponding Graph/Chart).....III-101$200
   Table 19: Japanese 15-Year Perspective for Gene Amplification Technologies by Segment – Percentage Breakdown of Dollar Sales for Polymerase Chain Reaction (PCR) and Other Gene Amplification Markets for Years 2003, 2011 & 2017 (includes corresponding Graph/Chart).....III-111$200
  4. EUROPE.....III-126 $950  
   Market Analysis.....III-12
Table 20: European Recent Past, Current & Future Analysis for Gene Amplification Technologies by Geographic Region – France, Germany, UK, Italy, and Rest of Europe Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2009 through 2017 (includes corresponding Graph/Chart).....III-12
1$200
   Table 21: European Historic Review for Gene Amplification Technologies by Geographic Region – France, Germany, UK, Italy, and Rest of Europe Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2003 through 2008 (includes corresponding Graph/Chart).....III-131$200
   Table 22: European 15-Year Perspective for Gene Amplification Technologies by Geographic Region – Percentage Breakdown of Dollar Sales for France, Germany, UK, Italy, & Rest of Europe Markets for Years 2003, 2011 & 2017 (includes corresponding Graph/Chart).....III-141$200
   Table 23: European Recent Past, Current & Future Analysis for Gene Amplification Technologies by Segment – Polymerase Chain Reaction (PCR) and Other Gene Amplification Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2009 through 2017 (includes corresponding Graph/Chart).....III-151$200
   Table 24: European Historic Review for Gene Amplification Technologies by Segment – Polymerase Chain Reaction (PCR) and Other Gene Amplification Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2003 through 2008 (includes corresponding Graph/Chart).....III-161$200
   Table 25: European 15-Year Perspective for Gene Amplification Technologies by Segment – Percentage Breakdown of Dollar Sales for Polymerase Chain Reaction (PCR) and Other Gene Amplification Markets for Years 2003, 2011 & 2017 (includes corresponding Graph/Chart).....III-171$200
  4a. FRANCE.....III-183 $495  
   Market Analysis.....III-18
Table 26: French Recent Past, Current & Future Analysis for Gene Amplification Technologies by Segment – Polymerase Chain Reaction (PCR) and Other Gene Amplification Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2009 through 2017 (includes corresponding Graph/Chart).....III-18
1$200
   Table 27: French Historic Review for Gene Amplification Technologies by Segment – Polymerase Chain Reaction (PCR) and Other Gene Amplification Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2003 through 2008 (includes corresponding Graph/Chart).....III-191$200
   Table 28: French 15-Year Perspective for Gene Amplification Technologies by Segment – Percentage Breakdown of Dollar Sales for Polymerase Chain Reaction (PCR) and Other Gene Amplification Markets for Years 2003, 2011 & 2017 (includes corresponding Graph/Chart).....III-201$200
  4b. GERMANY.....III-213 $495  
   Market Analysis.....III-21
Table 29: German Recent Past, Current & Future Analysis for Gene Amplification Technologies by Segment – Polymerase Chain Reaction (PCR) and Other Gene Amplification Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2009 through 2017 (includes corresponding Graph/Chart).....III-21
1$200
   Table 30: German Historic Review for Gene Amplification Technologies by Segment – Polymerase Chain Reaction (PCR) and Other Gene Amplification Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2003 through 2008 (includes corresponding Graph/Chart).....III-221$200
   Table 31: German 15-Year Perspective for Gene Amplification Technologies by Segment – Percentage Breakdown of Dollar Sales for Polymerase Chain Reaction (PCR) and Other Gene Amplification Markets for Years 2003, 2011 & 2017 (includes corresponding Graph/Chart).....III-231$200
  4c. ITALY.....III-243 $495  
   Market Analysis.....III-24
Table 32: Italian Recent Past, Current & Future Analysis for Gene Amplification Technologies by Segment – Polymerase Chain Reaction (PCR) and Other Gene Amplification Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2009 through 2017 (includes corresponding Graph/Chart).....III-24
1$200
   Table 33: Italian Historic Review for Gene Amplification Technologies by Segment – Polymerase Chain Reaction (PCR) and Other Gene Amplification Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2003 through 2008 (includes corresponding Graph/Chart).....III-251$200
   Table 34: Italian 15-Year Perspective for Gene Amplification Technologies by Segment – Percentage Breakdown of Dollar Sales for Polymerase Chain Reaction (PCR) and Other Gene Amplification Markets for Years 2003, 2011 & 2017 (includes corresponding Graph/Chart).....III-261$200
  4d. THE UNITED KINGDOM.....III-273 $495  
   Market Analysis.....III-27
Table 35: UK Recent Past, Current & Future Analysis for Gene Amplification Technologies by Segment – Polymerase Chain Reaction (PCR) and Other Gene Amplification Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2009 through 2017 (includes corresponding Graph/Chart).....III-27
1$200
   Table 36: UK Historic Review for Gene Amplification Technologies by Segment – Polymerase Chain Reaction (PCR) and Other Gene Amplification Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2003 through 2008 (includes corresponding Graph/Chart).....III-281$200
   Table 37: UK 15-Year Perspective for Gene Amplification Technologies by Segment – Percentage Breakdown of Dollar Sales for Polymerase Chain Reaction (PCR) and Other Gene Amplification Markets for Years 2003, 2011 & 2017 (includes corresponding Graph/Chart).....III-291$200
  4e. REST OF EUROPE.....III-303 $495  
   Market Analysis.....III-30
Table 38: Rest of Europe Market for Gene Amplification Technologies - Recent Past, Current & Future Market Analysis by Segment for Polymerase Chain Reaction (PCR) and Other Gene Amplification Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2009 through 2017 (includes corresponding Graph/Chart).....III-30
1$200
   Table 39: Rest of Europe Historic Review for Gene Amplification Technologies by Segment – Polymerase Chain Reaction (PCR) and Other Gene Amplification Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2003 through 2008 (includes corresponding Graph/Chart).....III-311$200
   Table 40: Rest of Europe 15-Year Perspective for Gene Amplification Technologies by Segment – Percentage Breakdown of Dollar Sales for Polymerase Chain Reaction (PCR) and Other Gene Amplification Markets for Years 2003, 2011 & 2017 (includes corresponding Graph/Chart).....III-321$200
  5. REST OF WORLD.....III-333 $495  
   Market Analysis.....III-33
Table 41: Rest of World Market for Gene Amplification Technologies - Recent Past, Current & Future Market Analysis by Segment for Polymerase Chain Reaction (PCR) and Other Gene Amplification Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2009 through 2017 (includes corresponding Graph/Chart).....III-33
1$200
   Table 42: Rest of World Historic Review for Gene Amplification Technologies by Segment – Polymerase Chain Reaction (PCR) and Other Gene Amplification Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2003 through 2008 (includes corresponding Graph/Chart).....III-341$200
   Table 43: Rest of World 15-Year Perspective for Gene Amplification Technologies by Segment – Percentage Breakdown of Dollar Sales for Polymerase Chain Reaction (PCR) and Other Gene Amplification Markets for Years 2003, 2011 & 2017 (includes corresponding Graph/Chart).....III-351$200
IV. COMPETITIVE LANDSCAPE 410$995
  
Total Companies Profiled: 90 (including Divisions/Subsidiaries - 104)

Region/Country                 Players

The United States                 60
Canada                             4
Japan                              4
Europe                            34 
     France                        4
     Germany                       5
     The United Kingdom           15 
     Italy                         1
     Spain                         2
     Rest of Europe                7
Asia-Pacific (Excluding Japan)     2
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