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  GENE AMPLIFICATION TECHNOLOGIES
A Global Strategic Business Report

This report analyzes the worldwide markets for Gene Amplification Technologies in Millions of US$. The major product segments analyzed are Polymerase Chain Reaction, and Other Gene Amplification Technologies. The report provides separate comprehensive analytics for the US, Canada, Japan, Europe, and Rest of World. Annual forecasts are provided for each region for the period of 2000 through 2010. The report profiles 109 companies including many key and niche players worldwide such as Applied Biosystems, Abbott Laboratories, Vysis Inc, Bio Merieux, Biotecon Diagnostics, Bio-Rad Laboratories, Cepheid, Eppendorf, GE Healthcare, QIAGEN N.V, Roche Diagnostics, Rubicon Genomics, Stratagene, Takara Shuzo co., Ltd., Thermo Electron Molecular Biology, Techne Inc. and Third Wave Technologies. Market data and analytics are derived from primary and secondary research. Company profiles are mostly extracted from URL research and reported select online sources.

CODE:    MCP-1102  PAGES:    427
PRICE:    $3950  DATE:       February 2006
COMPANIES:  109  MARKET DATA TABLES:   95
Due to the proprietary nature, our previews are offered only to manufacturers, top-tier management consultants, investment banks, and investment research groups.

 TABLE OF CONTENTS  
  GENE AMPLIFICATION TECHNOLOGIES (Complete Report) Pages : 427   | $3950
I. INTRODUCTION, METHODOLOGY & PRODUCT DEFINITIONS3$100
II. EXECUTIVE SUMMARY39$2150
  1. Industry Overview.....II-12 $200  
   PCR Dominates Amplification Technologies .....II-11$100
   Miniaturization – The Next Big Focus.....II-2
Gene Amplification Technology- Backbone of Human Genome Project .....II-2
Critical in Diagnostic Procedures.....II-2
Leading Players.....II-2
1$100
  2. Technology Overview.....II-311 $950  
   Definition of Gene Amplification.....II-3
Target vs. Signal Amplification .....II-3
Available Types of Gene Amplification Technologies.....II-3
Polymerase Chain Reaction .....II-3
1$100
   Reagents and Equipment required for PCR .....II-4
Reaction Steps.....II-4
Denaturation.....II-4
Annealing.....II-4
Extension.....II-4
1$100
   Detection of Amplified Product/DNA .....II-5
(Q&Q) PCR.....II-5
1$100
   Novel PCR Methods .....II-6
LightCycler RT- PCR Systems .....II-6
Reverse Transcriptase PCR (RT-PCR).....II-6
RT-PCR Enzymes .....II-6
Major companies offering RT-PCR Enzymes.....II-6
1$100
   Alternative Technologies to PCR.....II-7
OmniPlex .....II-7
Genome-wide Disease Association Studies.....II-7
Pharmacogenomics Studies.....II-7
Molecular Diagnostics and Forensics.....II-7
Additional OmniPlex Applications in Development.....II-7
Strand Displacement Amplification.....II-7
1$100
   Ligase Chain Reaction .....II-8
LCR Involves a Cyclic Two-Step Reaction.....II-8
Gene Amplification Technology (GAT).....II-8
Hybrid Capture .....II-8
1$100
   HC2.....II-9
HC3.....II-9
HC-EAS.....II-9
1$100
   Advantages of HC technology.....II-10
Sensitivity.....II-10
Intra-Slide and Inter-Slide Reproducibility.....II-10
Isothermal DNA Amplification Techniques.....II-10
Rolling circle Amplification in Diagnostics.....II-10
Companies and Research Centers into RCA Diagnostics.....II-10
Basics of RCA in DNA Diagnostics .....II-10
1$100
   Applications of RCA.....II-11
RCAT-immunodiagnostics.....II-11
Ican Isothermal Gene Amplification Technology.....II-11
1$100
   Other Amplification Technologies .....II-12
Signal Amplification Technology .....II-12
Transcription Mediated Amplification .....II-12
DNA cleavage-based signal amplification.....II-12
Invader Technology From TWT.....II-12
Ramification Amplification Method.....II-12
2$200
  3. End Use Market Analysis.....II-146 $600  
   Medical and Diagnostics .....II-14
Role of Amplification Technology in Diagnostics of Infectious Diseases .....II-14
Diagnosis of Infectious Diseases by PCR.....II-14
1$100
   Detection of Antimicrobial Resistance.....II-15
PCR Based Nucleic Acid Amplification for Detection of Antimicrobial Agents .....II-15
1$100
   Nucleic Acid Amplification Testing (NAT).....II-16
Nucleic Acid Amplification Methods Available in the Market.....II-16
The HCV RNA Testing .....II-16
Recent Patents in Nucleic Acid Amplification .....II-16
2$200
   Sysmex Introduces New Gene Amplification Detection Technologies.....II-18
Advantages and Limitations of DNA Amplification Technology in the Diagnosis of
  Infectious Diseases.....II-18
Forensic and Paternity .....II-18
1$100
   Food Safety.....II-19
1$100
  4. Research and Development.....II-201 $100  
   HC – More Precise Predictor than HercepTest.....II-20
ITF - Target of Gene Amplification in Melanoma.....II-20
1$100
  5. Product Launches.....II-213 $300  
   QIAGEN Rolls Out Wide RNAi and SYBR® Green-based RT- PCR.....II-21
Applied Biosystems Launches 7500 Fast Real-Time PCR System .....II-21
Applied Biosystems Launches 9800 Fast PCR System.....II-21
7900HT Fast Real-Time PCR System from Applied Biosystems.....II-21
1$100
   Enzo Life Sciences Introduces New Advanced Amplification Technology .....II-22
Applied Biosystems Unveils AmpFSTR® Yfiler™ PCR Amplification Kit.....II-22
Sysmex Introduces GD-100.....II-22
1$100
   Amersham Launches GenomiPhi .....II-23
Rubicon Genomics Launches GenomePlex WGA.....II-23
Agilent Introduces Amplification Kit .....II-23
Linden Introduces Snapshot mRNA.....II-23
Rubicon Launches OmniPlex™ .....II-23
1$100
  6. Recent Industry Activity.....II-247 $700  
   Sigma-Aldrich Acquires JRH.....II-24
Sigma-Aldrich Snaps Up Proligo.....II-24
Beckman to Acquire Agencourt.....II-24
Nanogen Inks Licensing Agreement with Pathway.....II-24
Nanogen Signs Agreement with decode.....II-24
Roche Diagnostics and Applera Corporation Expand PCR Licensing Program.....II-24
1$100
   Nanogen Receives Patents.....II-25
Mount and Hamilton Receive Patent.....II-25
Invitrogen Bags License from Applied Biosystems.....II-25
Sanko Attains Patents.....II-25
Applied Imaging Obtains 510(k) Clearance from FDA.....II-25
OriGene to Access TrueClone.....II-25
1$100
   Agilent to Offer Genomics in India.....II-26
Orchid BioSciences to Turn into Orchid Cellmark .....II-26
Spectral acquires Bacterial Barcodes.....II-26
QIAGEN Purchases Assets of Molecular Staging.....II-26
Sigma-Aldrich Partners Ingex.....II-26
Cepheid, Applied Biosystems and Celera Diagnostics Sign Patent License
  Agreement.....II-26
1$100
   Abbott Enters into Agreement with BioGenex.....II-27
Roche Inks Licensing Agreement with Incyte Corp.....II-27
Rubicon Genomics Signs Licensing Agreement with Sigma-Aldrich.....II-27
BioMérieux Teams-up with Cepheid .....II-27
Molecular Staging Collaborates with Eli Lilly .....II-27
Pacific Biometrics Inc. Receives Gene Amplification Patent .....II-27
1$100
   Rubicon Introduces Service for Genome Amplification .....II-28
Rubicon Provides Amplification Technology to Wellcome Trust .....II-28
Takara Obtains Patent for New Amplification Method.....II-28
Roche Signs Agreement with Qiagen GmbH.....II-28
Roche Diagnostics Strikes a Deal with Innogenetics N.V.....II-28
Idaho Receives Contract for PCR .....II-28
Nanosphere Signs Agreement with Takara .....II-28
1$100
   Eiken Acquires US Patent.....II-29
Bio-Rad Laboratories Offers DNA Amplification Technology to Specialty
  Laboratories.....II-29
Vysis Obtains Registration for HER-2 Gene Amplification in Breast Cancer.....II-29
NIGMA Grants Award to Ambion for RNA Amplification .....II-29
Molecular Staging Receives Three Patents for Rolling Circle Amplification
  Technology.....II-29
1$100
   NuGEN Develops Ribi-SPIA™ of RNA Amplification .....II-30
Phenix Research Products Launches DNA Amplification System .....II-30
Takara Gains Exclusive Rights to Sell Gene Amplification Equipment from Cepheid
  .....II-30
Gene Tec's Licenses Gene Amplification Method to Applied Biosystems.....II-30
Incyte Awards License to Merck & Co.....II-30
1$100
  7. Focus on Select Global Players.....II-316 $600  
   Applied Biosystems (US).....II-31
Abbott Laboratories (US).....II-31
Vysis Inc (US)......II-31
1$100
   Bio Merieux (France) .....II-32
Biotecon Diagnostics (Germany).....II-32
Bio-Rad Laboratories (US).....II-32
1$100
   Cepheid (US).....II-33
Eppendorf (Germany).....II-33
GE Healthcare (US).....II-33
1$100
   QIAGEN N.V (The Netherlands).....II-34
Roche Diagnostics (Switzerland).....II-34
1$100
   Rubicon Genomics (US).....II-35
Stratagene (US) .....II-35
Takara Shuzo co., Ltd. (Japan).....II-35
1$100
   Thermo Electron Molecular Biology (UK).....II-36
Techne Inc (UK).....II-36
Third Wave Technologies (US).....II-36
1$100
  8. Global Market Perspective.....II-37   
   Table 1: World Recent Past, Current & Future Market Analysis for Gene Amplification Technologies by Geographic Region – US, Canada, Japan, Europe, and Rest of World Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart).....II-37

Table 2: World 10-Year Perspective for Gene Amplification Technologies by Geographic Region – Percentage Breakdown of Dollar Sales for US, Canada, Japan, Europe, and Rest of World Markets for Years 2000, 2005 & 2010 (includes corresponding Graph/Chart).....II-37
1$300
   Table 3: World Recent Past, Current & Future Market Analysis for Polymerase Chain Reaction (PCR) by Geographic Region – US, Canada, Japan, Europe, and Rest of World Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart).....II-38

Table 4: World 10-Year Perspective for Polymerase Chain Reaction (PCR) by Geographic Region – Percentage Breakdown of Dollar Sales for US, Canada, Japan, Europe, and Rest of World Markets for Years 2000, 2005 & 2010 (includes corresponding Graph/Chart).....II-38
1$300
   Table 5: World Recent Past, Current & Future Market Analysis for Other Gene Amplification Technologies by Geographic Region – US, Canada, Japan, Europe, and Rest of World Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart).....II-39

Table 6: World 10-Year Perspective for Other Gene Amplification Technologies by Geographic Region – Percentage Breakdown of Dollar Sales for US, Canada, Japan, Europe, and Rest of World Markets for Years 2000, 2005 & 2010 (includes corresponding Graph/Chart).....II-39
1$300
III. MARKET31$1950
  1. The United States.....III-114 $925  
   A. Market Analysis .....III-1
Focus on Key Players .....III-1
Abbott Laboratories .....III-1
Vysis Inc......III-1
1$75
   Applied Biosystems .....III-2
Bio-Rad Laboratories.....III-2
Cepheid .....III-2
1$75
   GE Healthcare.....III-3
ID Biomedical Corp., .....III-3
Rubicon Genomics .....III-3
1$75
   Stratagene.....III-4
Third Wave Technologies.....III-4
Product Launches.....III-4
3$225
   Strategic Developments.....III-77$525
   B. Market Analytics.....III-14
Table 7: US Recent Past, Current & Future Analysis for Gene Amplification Technologies by Segment – Polymerase Chain Reaction (PCR) and Other Gene Amplification Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart).....III-14

Table 8: US 10-Year Perspective for Gene Amplification Technologies by Segment – Percentage Breakdown of Dollar Sales for Polymerase Chain Reaction (PCR) and Other Gene Amplification Markets for 2000, 2005 & 2010).....III-14
1$150
  2. Canada.....III-151 $150  
   Market Analysis .....III-15
Table 9: Canadian Recent Past, Current & Future Analysis for Gene Amplification Technologies by Segment – Polymerase Chain Reaction (PCR) and Other Gene Amplification Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart).....III-15

Table 10: Canadian 10-Year Perspective for Gene Amplification Technologies by Segment – Percentage Breakdown of Dollar Sales for Polymerase Chain Reaction (PCR) and Other Gene Amplification Markets for 2000, 2005 & 2010.....III-15
1$150
  3. Japan .....III-162 $150  
   A. Market Analysis .....III-16
Takara Shuzo Co., Ltd. – A Key Japanese Player.....III-16
Product Launch.....III-16
Strategic Developments.....III-16
1$75
   B. Market Analytics.....III-17
Table 11: Japanese Recent Past, Current & Future Analysis for Gene Amplification Technologies by Segment – Polymerase Chain Reaction (PCR) and Other Gene Amplification Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart).....III-17

Table 12: Japanese 10-Year Perspective for Gene Amplification Technologies by Segment – Percentage Breakdown of Dollar Sales for Polymerase Chain Reaction (PCR) and Other Gene Amplification Markets for 2000, 2005 & 2010.....III-17
1$150
  4. Europe .....III-183 $325  
   Market Analysis.....III-18
Table 13: European Recent Past, Current & Future Analysis for Gene Amplification Technologies by Geographic Region – France, Germany, UK, Italy, and Rest of Europe Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart).....III-18
1$150
   Table 14: European Recent Past, Current & Future Analysis for Gene Amplification Technologies by Segment – Polymerase Chain Reaction (PCR) and Other Gene Amplification Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart).....III-19

Table 15: European 10-Year Perspective for Gene Amplification Technologies by Geographic Region – Percentage Breakdown of Dollar Sales for France, Germany, UK, Italy, & Rest of Europe Markets for Years 2000, 2005 & 2010 (includes corresponding Graph/Chart).....III-19
1$150
   Table 16: European 10-Year Perspective for Gene Amplification Technologies by Segment – Percentage Breakdown of Dollar Sales for Polymerase Chain Reaction (PCR) and Other Gene Amplification Markets for 2000, 2005 & 2010.....III-20
1$150
  4a. France .....III-212 $150  
   A. Market Analysis.....III-21
Bio Merieux – A Key French Player.....III-21
1$75
   B. Market Analytics.....III-22
Table 17: French Recent Past, Current & Future Analysis for Gene Amplification Technologies by Segment – Polymerase Chain Reaction (PCR) and Other Gene Amplification Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart).....III-22

Table 18: French 10-Year Perspective for Gene Amplification Technologies by Segment – Percentage Breakdown of Dollar Sales for Polymerase Chain Reaction (PCR) and Other Gene Amplification Markets for 2000, 2005 & 2010.....III-22
1$150
  4b. Germany.....III-232 $150  
   A. Market Analysis.....III-23
Focus on Select Players .....III-23
Eppendorf .....III-23
Biotecon Diagnostics.....III-23
1$75
   B. Market Analytics.....III-24
Table 19: German Recent Past, Current & Future Analysis for Gene Amplification Technologies by Segment – Polymerase Chain Reaction (PCR) and Other Gene Amplification Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart).....III-24

Table 20: German 10-Year Perspective for Gene Amplification Technologies by Segment – Percentage Breakdown of Dollar Sales for Polymerase Chain Reaction (PCR) and Other Gene Amplification Markets for 2000, 2005 & 2010.....III-24
1$150
  4c. United Kingdom .....III-252 $150  
   A. Market Analysis .....III-25
Focus on Select Players.....III-25
Thermo Hybaid .....III-25
Techne Inc .....III-25
1$75
   B. Market Analytics.....III-26
Table 21: UK Recent Past, Current & Future Analysis for Gene Amplification Technologies by Segment – Polymerase Chain Reaction (PCR) and Other Gene Amplification Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart).....III-26

Table 22: UK 10-Year Perspective for Gene Amplification Technologies by Segment – Percentage Breakdown of Dollar Sales for Polymerase Chain Reaction (PCR) and Other Gene Amplification Markets for 2000, 2005 & 2010.....III-26
1$150
  4d. Italy.....III-271 $150  
   Market Analysis.....III-27
Table 23: Italian Recent Past, Current & Future Analysis for Gene Amplification Technologies by Segment – Polymerase Chain Reaction (PCR) and Other Gene Amplification Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart).....III-27

Table 24: Italian 10-Year Perspective for Gene Amplification Technologies by Segment – Percentage Breakdown of Dollar Sales for Polymerase Chain Reaction (PCR) and Other Gene Amplification Markets for 2000, 2005 & 2010.....III-27
1$150
  4e. Rest of Europe.....III-283 $200  
   A. Market Analysis .....III-28
Product Launch.....III-28
Focus on Key Players.....III-28
QIAGEN N.V (Netherlands).....III-28
1$75
   Roche Diagnostics (Switzerland).....III-291$75
   B. Market Analytics .....III-30
Table 25: Rest of Europe Market for Gene Amplification Technologies - Recent Past, Current & Future Market Analysis by Segment for Polymerase Chain Reaction (PCR) and Other Gene Amplification Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart).....III-30

Table 26: Rest of Europe 10-Year Perspective for Gene Amplification Technologies by Segment – Percentage Breakdown of Dollar Sales for Polymerase Chain Reaction (PCR) and Other Gene Amplification Markets for 2000, 2005 & 2010.....III-30
1$150
  5. Rest of World.....III-312 $150  
   Market Analysis .....III-31
Table 27: Rest of World Market for Gene Amplification Technologies - Recent Past, Current & Future Market Analysis by Segment for Polymerase Chain Reaction (PCR) and Other Gene Amplification Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart).....III-31

Table 28: Rest of World 10-Year Perspective for Gene Amplification Technologies by Segment – Percentage Breakdown of Dollar Sales for Polymerase Chain Reaction (PCR) and Other Gene Amplification Markets for 2000, 2005 & 2010.....III-31
1$150
IV. COMPETITIVE LANDSCAPE345$995
  
Total Companies Profiled: 109 (including Divisions/Subsidiaries - 122 )

Region/Country                 Players

The United States                  71
Canada                              4
Japan                               4
Europe                             40
     France                         4
     Germany                        5
     The United Kingdom            17
     Italy                          1
     Spain                          2
     Rest of Europe                11
Asia-Pacific (Excluding Japan)      3
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Due to the proprietary nature, our previews are offered only to manufacturers, top-tier management consultants, investment banks, and investment research groups.

© Copyrights 2008, Global Industry Analysts, Inc., USA.