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  BRACHYTHERAPY
A Global Strategic Business Report

This report analyzes the Global Market for Brachytherapy in Millions of US$ by the following product segments: Implantable Prostate Seeds Brachytherapy, and Post-Operative Brachytherapy. Annual forecasts are provided for the period 2005 through 2015. The report profiles 38 companies including many key and niche players worldwide such as Best Medical International, Inc., Best Vascular, Inc., BrachySciences, Inc., Core Oncology, C. R. Bard, Inc., Cytyc Corporation, Eckert & Ziegler Strahlen- und Medizintechnik AG, International Brachytherapy SA, NAS Medical, Oncura, Inc., Sirtex Medical Ltd., Theragenics Corporation, Varian Medical Systems, Inc., and Xoft, Inc. Market data and analytics are derived from primary and secondary research. Company profiles are mostly extracted from URL research and reported select online sources.

CODE:    MCP-1834  PAGES:    233
PRICE:    $3950  DATE:       July 2009
COMPANIES:  38  MARKET DATA TABLES:   87
Due to the proprietary nature, our previews are offered only to manufacturers, top-tier management consultants, investment banks, and investment research groups.

 TABLE OF CONTENTS  
  BRACHYTHERAPY (Complete Report) Pages : 233   | $3950
I......INTRODUCTION, METHODOLOGY & PRODUCT DEFINITION4$100
   Study Reliability and Reporting Limitations.....I-1  
   Disclaimers.....I-2
Data Interpretation & Reporting Level.....I-2
  
   Quantitative Techniques & Analytics.....I-3
Product Definition and Scope of Study.....I-3
Implantable Prostate Seeds Brachytherapy.....I-3
  
   Post-Operative Brachytherapy.....I-4  
II. EXECUTIVE SUMMARY61$2250
  1. INDUSTRY OVERVIEW.....II-13 $700  
   Cancer – A Major Health Concern.....II-1
Quick Cancer Statistics.....II-1
1$100
   Table 1: Worldwide New Cancer Cases (2007) – Percentage Share Breakdown by Region (includes corresponding Graph/Chart).....II-2

Table 2: Worldwide New Cancer Cases (2007) – Percentage Share by Region and Sex (includes corresponding Graph/Chart).....II-2
Growing Cancer Cases in Developing Countries.....II-2
1$300
   Table 3: Worldwide Cancer Causes (%) by Level of Economic Development (includes corresponding Graph/Chart).....II-3
1$300
  2. BRACHYTHERAPY MARKET.....II-44 $400  
   Brachytherapy - A Prelude.....II-4
Growth Driving Factors.....II-4
Brachytherapy Provides Hope for Cancer Patients.....II-4
1$100
   Growing Brachytherapy Acceptance.....II-5
Aging Population: An Important Demographic Driver.....II-5
Prostate Brachytherapy Offers Bright Prospects.....II-5
1$100
   Reimbursement Scenario.....II-6
Competition Heats Up in the Brachytherapy Market.....II-6
1$100
   Macular Degeneration – An Emerging Brachytherapy Application.....II-7
APBI Therapy Rise in Popularity.....II-7
Balloon Brachytherapy Gains Prominence.....II-7
1$100
  3. BRACHYTHERAPY – AN INTRODUCTION.....II-88 $600  
   What is Brachytherapy?.....II-8
Implantable Prostate Seeds Brachytherapy.....II-8
Post-Operative Brachytherapy.....II-8
Mechanism of Action.....II-8
1$100
   Brachytherapy – Under the Microscope.....II-9
Brachytherapy Sources.....II-9
1$100
   The Team.....II-10
Historical Perspective.....II-10
Brachytherapy – A Classification.....II-10
Types As Per Seed Positioning.....II-10
Mold Brachytherapy.....II-10
Interstitial Brachytherapy.....II-10
1$100
   Endovascular Brachytherapy.....II-11
Stent-Based Techniques.....II-11
Catheter-Based Techniques.....II-11
1$100
   Intracavitary Brachytherapy.....II-12
Classification As Per Irradiation Duration.....II-12
Temporary Brachytherapy.....II-12
Permanent Brachytherapy.....II-12
1$100
   Categorization As Per the Dose Rate.....II-13
HDR Brachytherapy.....II-13
LDR Brachytherapy.....II-13
1$100
   PDR Brachytherapy.....II-14
PDR Brachytherapy Vs HDR Brachytherapy.....II-14
1$100
   PDR Brachytherapy Vs LDR Brachytherapy.....II-15
1$100
  4. BRACHYTHERAPY EQUIPMENT.....II-162 $200  
   Brachytherapy Systems.....II-16
Remote Afterloading Machines.....II-16
Manual Afterloading Machines.....II-16
1$100
   Brachytherapy Applicators.....II-17
Types of Brachytherapy Applicators.....II-17
Automated Brachytherapy Applicators.....II-17
Manual Brachytherapy Applicators.....II-17
1$100
  5. PROSTATE CANCER – A MAJOR BRACHYTHERAPY INDICATION.....II-185 $500  
   Prostate Cancer – A Deadly Disease.....II-18
Brachytherapy Revolutionizes Prostate Cancer Treatment.....II-18
History Behind the Development.....II-18
1$100
   Prostate Brachytherapy Procedure.....II-19
Seed Brachytherapy Clinical Outcomes.....II-19
1$100
   Side Effects Do Exist.....II-201$100
   Types of Brachytherapy Procedures for Prostate Cancer Treatment.....II-21
Interstitial Brachytherapy.....II-21
Combination Radiotherapy.....II-21
1$100
   Whole Pelvic Radiation Therapy.....II-22
Seed Migration – A Cause of Concern?.....II-22
1$100
  6. OTHER MAJOR BRACHYTHERAPY INDICATIONS.....II-237 $500  
   Breast Cancer.....II-23
Breast Brachytherapy – An Introduction.....II-23
How is Breast Brachytherapy Performed?.....II-23
1$100
   Breast Brachytherapy Techniques.....II-241$100
   Brain Brachytherapy.....II-25
Brain Tumor.....II-25
Types of Brain Tumor.....II-25
Treatment Techniques.....II-25
Brain Brachytherapy.....II-25
1$100
   Whole Brain Radiation Therapy.....II-26
Bronchial Carcinoma.....II-26
Bronchial Brachytherapy.....II-26
1$100
   Procedure.....II-27
Head and Neck Brachytherapy.....II-27
1$100
   Cervical Brachytherapy.....II-28
Esophageal Brachytherapy.....II-28
Brachytherapy for Eyelid Tumors.....II-28
1$100
   Other Indications.....II-29
1$100
  7. RESEARCH/STUDY FINDINGS.....II-304 $400  
   CyberKnife® Effective for HDR Brachytherapy.....II-30
SAVI Breast Brachytherapy Offers Enhanced Dose Control.....II-30
Electronic Brachytherapy Treats Early Stage Breast Cancer.....II-30
1$100
   Brachytherapy Treats Head And Neck Cancers.....II-31
Brachytherapy and External Radiation Therapy Offer Impressive Outcomes.....II-31
1$100
   Brachytherapy Effective in Single Brain Metastases Treatment.....II-32
MRI-based Brachytherapy Treats Cervical Cancer.....II-32
2$200
  8. PRODUCT INNOVATIONS/INTRODUCTIONS.....II-346 $450  
   Varian Medical Systems Launch VariSeed 8.0.....II-34
Nucletron Introduces 3 New Brachytherapy Products.....II-34
Xoft to Launch Axxent Xpress™ Mobile Electronic Brachytherapy Vehicles.....II-34
1$100
   SenoRx Launches Contura Multi-Lumen Balloon Catheter.....II-35
BrachySciences Introduces TheraSeed® Palladium-103 Isotope AnchorSeed.....II-35
Cianna Medical Launches New Version of SAVI™ Applicator.....II-35
Nucletron Introduces Oncentra® Brachy Cancer Treatment Solution.....II-35
1$100
   Varian to Introduce New RapidArc Radiotherapy Technology.....II-36
Prowess Launches Inverse Planning Brachytherapy System.....II-36
1$100
   IBA Introduces New COMPACT Proton Therapy System.....II-37
Varian Introduces Brachytherapy Treatment Planning System.....II-37
Nucletron Unveils IPSA for HDR Brachytherapy.....II-37
1$100
   B-K Medical Introduces New Transducer.....II-38
FDA Approves NASI’s New Range of Brachytherapy Offerings.....II-38
NASI Launches ClearPath™.....II-38
1$100
   BioLucent Launches Innovative SAVI Device for Breast Brachytherapy.....II-39
1$100
  9. RECENT INDUSTRY ACTIVITY.....II-4014 $900  
   IsoRay and BrachySciences Ink Distribution Agreement.....II-40
North American Scientific Agrees to Divest Prostate Brachytherapy Products.....II-40
IsoRay Receives Health Canada’s Approval for Selling Proxcelan Cs-131.....II-40
1$100
   Nucletron Enters into Partnership with Isodose Control.....II-41
Xoft Gains FDA Approval for Applicators.....II-41
Varian Medical Collaborates with BK Medical.....II-41
1$100
   Oncologix Inks MoU with IUT.....II-42
NeoVista Gains Approval from BSI Product Services.....II-42
Xoft and Elekta Inks an Agreement.....II-42
IsoRay Acquires Minority Stake in UralDial.....II-42
1$100
   IBt-BEBIG Receives Supply Contract from Hospital Universitario Ramón y Cajal.....II-43
Eckert & Ziegler to Supply Radiation Therapy Products to Spanish Hospitals.....II-43
North American Scientific Changes Name to NAS Medical.....II-43
1$100
   Theragenics Acquires NeedleTech.....II-44
Implant to Divest IP and Medical Assets of Brachytherapy Products Business.....II-44
IBt to Form Joint Venture with RNT and 000 Bebig.....II-44
Nucletron and AKH/MUW Extend Cooperation with Multi-Tiered Partnership.....II-44
1$100
   IsoAid Secures 3-Year Contract for Supply of Brachytherapy Products.....II-45
Envisioneering Inks Distribution Agreement with Isodose Control.....II-45
Biocompatibles Acquires BrachySciences.....II-45
Nucletron and BrachySolutions Form Partnership.....II-45
1$100
   SIUT Inaugurates New Brachytherapy Center.....II-46
IBt to Acquire Brachytherapy Business Segments from EZAG.....II-46
North American Scientific Enters into an Agreement with Carbon Medical.....II-46
Varian Receives FDA Approval for Brachytherapy Applicator.....II-46
1$100
   IBt Completes Acquisition of Urorad.....II-47
IsoRay Inks an Agreement with Applied Process Engineering Laboratory.....II-47
International Brachytherapy Inks an Agreement with IBA.....II-47
1$100
   IsoRay Medical Inks Letter of Intent with International Brachytherapy.....II-48
IsoRay Medical to Shift Production Facility to APEL in Richland.....II-48
Radiation Therapy Services Acquires Radiation Therapy Facility.....II-48
1$100
   Hologic Plans BioLucent Acquisition.....II-49
Core Oncology Acquires Mills Biopharmaceuticals.....II-49
International Isotopes Takes Over Minority Stake in RadQual.....II-49
ONCURA Inks Agreement with Premier.....II-49
1$100
   MDS Nordion and Best Medical International Sign an Agreement.....II-50
North American Scientific Divests NOMOS® to Best Medical International.....II-50
Premier Renews Contract with North American Scientific.....II-50
Sirtex Expands its Research and Development Program.....II-50
1$100
   Xoft Axxent™ Electronic Brachytherapy System Receives FDA Approval.....II-51
North American Scientific Launches Initiative for Breast Brachytherapy.....II-51
Coloplast Acquires Urology Business Unit of Mentor.....II-51
Implant Sciences Signs an Agreement with International Brachytherapy.....II-51
1$100
   BrachySciences Enters into Distribution Agreement with Envisioneering.....II-52
IBt Inks a Distribution Agreement with Isodose Control.....II-52
ONCURA Inks an Agreement with Novation and UHC.....II-52
1$100
   ONCURA Inks an Agreement with HealthTrust Purchasing Group.....II-53
IsoRay Commences Cesium-131 Production Testing.....II-53
InterCommunity Cancer Center Offers Cesium-131 for Prostrate Cancer.....II-53
1$100
  10. OTHER DEVELOPMENTS.....II-543 $300  
   The U.S. Patent and Trademark Office Issues Patents for SAVI™.....II-54
Sirtex Obtains FDA Approval for Producing SIR-Spheres® Microspheres.....II-54
MDS Nordion Secures FDA Approval for TheraSphere®.....II-54
1$100
   Health Commission Wales to Provide Brachytherapy Services in Wales.....II-55
IBt Receives Reimbursement for InterStrand-125 and InterSource-125.....II-55
MDS Nordion Sets Up Centers of Excellence for TheraSphere®.....II-55
Aarhus University Hospital Begins Using IGBT.....II-55
1$100
   WellStar Kennestone Hospital Acquires Axxent Electronic Brachytherapy System.....II-56
Silicon Valley Urology Center Starts Using Cesium-131.....II-56
MDS Nordion Receives US FDA Approval to Test Efficacy of TheraSphere®.....II-56
ONCURA Bags Contract to Supply Seeds to The Cookridge Hospital.....II-56
1$100
  11. FOCUS ON SELECT GLOBAL PLAYERS.....II-575 $500  
   Best Medical International, Inc. (US).....II-57
Best Vascular, Inc. (US).....II-57
BrachySciences, Inc. (US).....II-57
Core Oncology (US).....II-57
1$100
   C. R. Bard, Inc. (US).....II-58
Cytyc Corporation (US).....II-58
Eckert & Ziegler Strahlen- und Medizintechnik AG (Germany).....II-58
1$100
   International Brachytherapy SA (Belgium).....II-59
NAS Medical (US).....II-59
Nucletron BV (The Netherlands).....II-59
Oncura, Inc. (US).....II-59
1$100
   Sirtex Medical Ltd. (Australia).....II-60
Theragenics Corporation (US).....II-60
Varian Medical Systems, Inc. (US).....II-60
1$100
   Xoft, Inc. (US).....II-611$100
III. MARKET45$1950
  1. THE UNITED STATES.....III-131 $1625  
   A. Market Analysis.....III-1
Current & Future Analysis.....III-1
Cancer Presumes Epidemic Proportion.....III-1
A Glance at Cancer Statistics.....III-1
1$75
   Table 4: Cancer-Affected Population in the US (2007): Percentage Share Breakdown by Cancer Type (includes corresponding Graph/Chart).....III-2

Table 5: US New Cancer Cases (2008) – Percentage Share Breakdown by Leading State (includes corresponding Graph/Chart).....III-2
1$150
   Growing Cancer Prevalence Drives Brachytherapy Demand.....III-3
Brachytherapy – Effective Option for Cancer Treatment.....III-3
1$75
   Rapid Growth in Prostate Brachytherapy Market.....III-4
Leading Players.....III-4
Table 6: Leading Players in the US Implantable Seeds Brachytherapy Market (2009E): Percentage Share Breakdown of Sales for Oncura Corp., CR Bard, and Others (includes corresponding Graph/Chart).....III-4
Technology Advancements Accelerate Growth.....III-4
1$150
   Breast Brachytherapy Witnesses Slow Growth.....III-5
Balloon Brachytherapy Making Inroads into Mainstream Market.....III-5
Competitive Scenario.....III-5
Table 7: US Balloon Brachytherapy Market (2008): Percentage Value Share Breakdown by Leading Company – Cytyc, SenoRx, and Xoft (includes corresponding Graph/Chart).....III-5
1$150
   Reimbursement Scenario.....III-6
Growth Drivers.....III-6
Positive Research Results Drive Acceptance of Brachytherapy.....III-6
1$75
   Market Consolidation Drives Growth.....III-7
New Developments Propel Market Growth.....III-7
1$75
   Product Launches.....III-85$375
   Strategic Corporate Developments.....III-138$450
   Other Developments.....III-213$225
   Key Players.....III-245$375
   B. Market Analytics.....III-29
Table 8: US Recent Past, Current & Future Analysis for Brachytherapy: Annual Number of Implantable Prostate Seed and Post-Operative Brachytherapy Procedures for Years 2005 through 2015 (in Thousands) (includes corresponding Graph/Chart).....III-29

Table 9: US 10-Year Perspective for Brachytherapy by Segment – Percentage Breakdown of Implantable Prostate Seed and Post-Operative Brachytherapy Procedures for Years 2006, 2009 & 2015.....III-29
1$150
   Table 10: US Recent Past, Current & Future Analysis for Brachytherapy by Segment – Implantable Prostate Seed and Post-Operative Brachytherapy Procedures Markets Independently Analyzed with Annual Revenues in US$ Million for Years 2005 through 2015 (includes corresponding Graph/Chart).....III-30

Table 11: US 10-Year Perspective for Brachytherapy by Segment – Percentage Breakdown of Revenues for Implantable Prostate Seed and Post-Surgical Brachytherapy Markets for Years 2006, 2009 & 2015.....III-30
1$150
   Table 12: US Recent Past, Current & Future Analysis for Endovascular Brachytherapy Market with Annual Revenues in US$ Million for Years 2005 through 2015 (includes corresponding Graph/Chart).....III-31
1$150
  2. EUROPE.....III-3214 $1050  
   A. Market Analysis.....III-32
Market Outlook.....III-32
Brachytherapy in Europe.....III-32
1$75
   Seed Brachytherapy Market – An Overview.....III-33
Strategic Initiatives to Drive Growth.....III-33
Leading Players.....III-33
Table 13: Leading Players in the European Implantable Prostate Seeds Market (Iodine) (2009E): Percentage Breakdown of Value Sales for Oncura Corp., C.R. Bard, and Others (includes corresponding Graph/Chart).....III-33
1$150
   Reimbursement Changes Accelerate Radiation Seed Sales.....III-34
Prostate Brachytherapy Gains Strength.....III-34
Prostate Seed Market.....III-34
An Overview.....III-34
Competitive Analysis.....III-34
1$75
   Seed Pricing Analysis.....III-35
Table 14: Average Prices of Prostate Brachytherapy Seeds for the years 2003 & 2010.....III-35
A Focus on the French Market.....III-35
UK Prostate Brachytherapy Market – An Overview.....III-35
1$150
   Strategic Corporate Developments.....III-366$450
   Key Players.....III-422$150
   B. Market Analytics.....III-44
Table 15: European Recent Past, Current & Future Analysis for Brachytherapy: Annual Number of Implantable Prostate Seed and Post-Operative Brachytherapy Procedures for Years 2005 through 2015 (in Thousands) (includes corresponding Graph/Chart).....III-44

Table 16: European 10-Year Perspective for Brachytherapy by Segment – Percentage Breakdown of Implantable Prostate Seed and Post-Operative Brachytherapy Procedures for Years 2006, 2009 & 2015.....III-44
1$150
   Table 17: European Recent Past, Current & Future Analysis for Brachytherapy by Segment – Implantable Prostate Seed and Post-Operative Brachytherapy Procedures Markets Independently Analyzed with Annual Revenues in US$ Million for Years 2005 through 2015 (includes corresponding Graph/Chart).....III-45

Table 18: European 10-Year Perspective for Brachytherapy by Segment – Percentage Breakdown of Annual Revenues for Implantable Prostate Seed and Post-Operative Brachytherapy Markets for Years 2006, 2009 & 2015.....III-45
1$150
IV. COMPETITIVE LANDSCAPE 115$995
  
Total Companies Profiled: 38 (including Divisions/Subsidiaries - 51)

Region/Country                 Players


The United States               32  
Canada                           1
Europe                          15
     Germany                     4
     The United Kingdom          2
     Italy                       1
     Rest of Europe              8
Asia-Pacific (Excluding Japan)   3
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Due to the proprietary nature, our previews are offered only to manufacturers, top-tier management consultants, investment banks, and investment research groups.

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