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BIOCOMPATIBLE MATERIALS - A GLOBAL STRATEGIC BUSINESS REPORT   

Research Abstract

This report analyzes the worldwide markets for Biocompatible Materials in US$ Million by the following product segments: Polymeric Materials, Metallic Materials, Natural Materials, and Other Materials. The report provides separate comprehensive analytics for the North America, Japan, Europe, and Rest of World. Annual estimates and forecasts are provided for the period 2007 through 2015. Also, a seven-year historic analysis is provided for these markets. The report profiles 68 companies including many key and niche players such as A.P. Pharma, Inc., Angiotech Pharmaceuticals Inc., Artimplant AB, AST Products, Inc., Biocoat, Inc., DENTSPLY International Inc., Invibio, Integra LifeSciences Holdings Corporation, Orthovita Inc., SaluMedica, LLC, SurModics, Synthes Inc., and United States Surgical. Market data and analytics are derived from primary and secondary research. Company profiles are mostly extracted from URL research and reported select online sources.

Code : MCP-1094
Price : $4500
Companies : 68
Pages : 364
Date : January 2011
Market Data Tables : 29

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 TABLE OF CONTENTS

  BIOCOMPATIBLE MATERIALS (Complete Report) Pages : 364   | $4500
 
  1. INTRODUCTION, METHODOLOGY & PRODUCT DEFINITIONS.......14 $295  
   Study Reliability and Reporting Limitations.......1  
   Disclaimers.......2  
   Data Interpretation & Reporting Level.......3
Quantitative Techniques & Analytics.......3
Product Definition and Scope of Study.......3
  
   Polymeric Materials.......4
Metallic Materials.......4
Natural Materials.......4
Other Materials.......4
  
  2. INDUSTRY OVERVIEW.....53 $295  
   Biocompatible Materials Market Continues to Surge, Despite Recession.....5
Current and Future Analysis.....5
Regional Perspective.....5
1$100
   Developing Regions to Propel Future Growth.....6
Material-Wise Perspective.....6
R&D Creates Brighter Avenues.....6
Competitive Scenario.....6
Factors Determining Market Growth.....6
Awareness of Basic Mechanisms of Cell-Material Interaction.....6
1$100
   Birth of Cross-Disciplinary Field of Tissue Engineering.....7
Rise in Biomaterial Prices.....7
Stem-Cell Technology – A Threat.....7
1$100
  3. PRODUCT TRENDS.....84 $395  
   Biomaterials Play Crucial Role in Implants Market.....8
Natural Substances find Increasing Application in Biomaterial Syntheses.....8
Plastic Companies Join the Fray as Manufacturers of Biodegradable Materials.....8
1$100
   Ceramic Fillings as Substitute for Silver-Tin-Mercury Amalgam Fillings.....9
Ceramics Offer Significant Potential in Crown Syntheses.....9
Hafnium – A Promising Material for Biocompatible Coatings.....9
Chitin as a New Biomaterial.....9
Bioglass - A Potential Material for Bone Regeneration.....9
1$100
   Collagen – An Efficient Biomaterial for Synthetic Vascular Grafts.....10
Biopolymers as Biomaterials.....10
Bioabsorbable Intelligent Materials.....10
Biocompatible Coatings – A Boon for Medical Implant Applications.....10
1$100
   Nanotechnology – Revolutionizes Development of Biomaterial Implants.....111$100
  4. END-USE MARKET ANALYSIS.....129 $950  
   Biosensors.....12
Implants .....12
Common Orthopedic Implants: Merits and Demerits.....12
1$100
   Biocompatibility of Implants with Blood.....13
Integrating Heparin to Polymeric Surface.....13
1$100
   Dental Implants.....14
Recession Decelerates Dental Implant Market, Outlook Remains Positive.....14
Significant Market Opportunities Exist for Dental Implants.....14
1$100
   Nanotechnology Permeates Dental Implant Market.....15
Competitive Scenario.....15
Table 1: Global Dental Implant Market by Leading Players (2009): Market Share Breakdown of Revenue for Nobel Biocare, Straumann, Biomet/3i, Zimmer Dental, Dentsply and Others (includes corresponding Graph/Chart).....15
1$350
   Joint Implant.....16
Artificial Organs.....16
Artificial Heart.....16
Totally Implantable Artificial Heart (TAH) System.....16
Pneumatic Total Artificial Heart (PTAH).....16
Cardiopulmonary Bypass System for Long-term Use.....16
Ventricular Assist Device.....16
Artificial Blood Vessels.....16
1$100
   Artificial Blood.....17
Artificial Skin.....17
Surface Coatings.....17
1$100
   Materials for Drug Delivery Systems.....18
Polyethylene Glycol as a Drug Delivery System.....18
Hydrogels as Drug Delivery System.....18
Vinylic based Drug Delivery Systems.....18
Collagen Based Drug Delivery System.....18
Electrodes.....18
1$100
   Tissue Replacement Materials.....19
Dialysis/Separation/Filtration Systems.....19
Dialysis.....19
1$100
   Filtration and Separation.....20
Cosmetic and Dental Materials.....20
Biomaterials for Cosmetic Formulations.....20
1$100
  5. RESEARCH AND DEVELOPMENT.....213 $295  
   Biocompatible Materials – Key Research Objectives.....211$100
   R&D Activity In the Recent Past.....22
French Inventors Develop Three-Dimensional Filet Stitch Fabric Wall
  Reinforcement.....22
California Inventor Develops Biocompatible Material.....22
Scientists Develop Process for Producing Biocompatible Fibers.....22
Penn State Researchers Develop New Niobium Molding Process.....22
Doxa Commences Clinical Trials for Novel Biomaterial.....22
1$100
   FzioMed Concludes Preliminary Study for Oxiplex Gel.....23
MIV’s Biomaterial Stent Coating Clears Pyrogen Clinical Testing.....23
1$100
  6. REGULATORY ENVIRONMENT.....24   
   FDA Regulations.....24
American Society for Testing and Materials (ASTM).....24
Joint Research Center (JRC).....24
Biocompatibility Testing of Materials.....24
Testing Levels.....24
General Biocompatibility Testing.....24
1$100
   Individual Biocompatibility Testing.....25
Testing Methods.....25
1$100
  7. PRODUCT OVERVIEW.....267 $595  
   Biocompatible Materials – An Introduction.....26
Definition of Biocompatible Materials.....26
Applications.....26
Orthopedic Applications.....26
Cardiovascular Applications.....26
1$100
   Dental Applications.....27
Biomaterials as Skin Replacements.....27
Biomaterials as Scaffolds for Tissue Engineering.....27
Product Segments.....27
Polymeric Materials.....27
1$100
   Hydrogels.....28
Biodegradable Polymers.....28
1$100
   Metallic Materials.....291$100
   Natural Materials.....30
Collagen.....30
Hyaluronic Acid.....30
Other Materials.....30
Ceramics.....30
1$100
   Bioactive Ceramics.....31
Applications.....31
Bone Substitutes.....31
Articulating Surfaces in Joint Implants.....31
Composites.....31
1$100
   Pyrolitic Carbon.....32
Biomaterial Segments and Applications: An Outline.....32
1$100
  8. PRODUCT INTRODUCTIONS/INNOVATIONS.....335 $395  
   Bayer MaterialScience Launches Baymedix Brand.....33
Exotech Bio Solutions Develops Super-Absorbent Polymers.....33
Wacker Launches Silpuran 6600.....33
Thermo Fisher Scientific Launches HyperSep Retain Polymers.....33
1$100
   Aesculap to Launch MonoMax Monofilament Absorbable Suture.....34
Lifecore Biomedical Launches Corgel BioHydrogel Research Hydrogel.....34
Incisive Surgical to Unveil Advanced INSORB® Absorbable Staple.....34
AGY Launches HPB Glass Fiber.....34
1$100
   DSM Biomedical Unveils Modern Application for ComfortCoat.....35
Medtronic Launches X-STOP PEEK IPD System.....35
K2M Enters into Biomaterials Sector.....35
Orthovita to Launch Vitoss Bioactive Foam Pack.....35
1$100
   Cook Medical Unveils Umbilical Hernia Graft.....36
Stratasys Launches ABS-M30i Biocompatible Material.....36
K2M Launches Aleutian AN and Aleutian Anterior.....36
2$200
  9. PRODUCT INTRODUCTIONS/INNOVATIONS IN RECENT PAST – A PERSPECTIVE BUILDER.....38   
   Invibio® Launches ENDOLIGN™ Polymer Composite.....38
Zimmer Dental Launches the Puros® Dermis Allograft Tissue Matrix.....38
Integra Launches Nerve Injury Products.....38
1$100
   DePuy Mitek Expands Orthopedics Product Portfolio.....39
DSM Dyneema Introduces Polyethylene Fiber.....39
1$100
  10. RECENT INDUSTRY ACTIVITY.....4010 $595  
   Piramal Healthcare to Acquire Assets of BioSyntech.....40
DSM Biomedical and CID Enter into Partnership.....40
Angiotech Acquires Haemacure's Technology Assets and Product Candidates.....40
1$100
   Sigma-Aldrich and Boehringer Ingelheim Pharma Ink Distribution Agreement.....41
ETEX Corporation's CarriGen Receives FDA Approval.....41
FDA Approves Custom Spine's PATHWAY ACIF.....41
1$100
   Bayer Material Science Acquires PolyBioMed.....42
Allergan Snaps Up Serica Technologies.....42
ETEX and Orthopediatrics Enter Distribution Agreement.....42
Anika Therapeutics Takes Over Fidia Advanced Biopolymers.....42
1$100
   TiGenix Acquires Orthomimetics.....43
ETEX Corporation and Alphatec Spine Sign Distribution Agreement.....43
NeuroVasx's cPAX Receives Canadian Approval.....43
PolyMedix Receives Grant for Developing Anti-Bacterial Materials.....43
1$100
   Synovis Life Technologies Acquires Assets of Pegasus Biologics.....44
Immuno-Biological laboratories to Purchase NEOSILK.....44
NMT Medical Obtains Pre-Market Approval.....44
Xiros Launches Research Laboratory.....44
SyntheMed Receives Pre-Market approval for REPEL-CV Adhesion Barrier.....44
1$100
   Neovasc Enters into Agreement with LeMaitre Vascular.....45
Healionics Inks Agreement with TR BioSurgical.....45
Xceed Capital Raises Stake in PolyNovo Biomaterials.....45
1$100
   CorMatrix Cardiovascular Receives Clearance for ECM™ Technology.....46
OPKO Health Takes Over Vidus Ocular.....46
Royal DSM NV to Acquire DSM PTG.....46
ETEX Signs Supply Agreement with AllloSource.....46
1$100
   Orthovita and Medafor Enter into Distribution Agreement.....47
Bio-Bridge Signs Memorandum of Understanding with JR Scientific.....47
Etex Inks Supply Agreement with LifeNet Health.....47
1$100
   Heparinex and Choncept Sign Option/License Agreement with Biological E......48
LeMaitre Acquires Biomateriali.....48
Angiotech Pharmaceuticals inks Licensing Agreement with Symphony Medical.....48
1$100
   Vertellus Biomaterials Signs License and Supply Agreement.....491$100
  11. INDUSTRY ACTIVITY IN THE RECENT PAST – A PERSPECTIVE BUILDER.....505 $395  
   Tyco International Acquires Confluent Surgical.....50
SurModics Acquires Intralytix’s Biodegradable Polymer Technology.....50
Orthovita Signs a Collaboration Agreement with Aastrom Biosciences for Orthopedic
  Products.....50
Kuhnil Pharma Acquires Rights from BioSyntech.....50
SurModics Licenses Hydrophilic Coating to Devax.....50
1$100
   BioSyntech Receives Notice of Allowance from the US Patent and Trademark Office for
  BST-CarGel®.....51
Artimplant Signs License and Development Agreements with Small Bone
  Innovations.....51
SaluMedica Licenses Proprietary Biomaterial to Spine Medica.....51
SurModics Licenses Hydrophilic Technology to Medtronic.....51
SurModics Obtains Exclusive Rights from Rutgers University to Biodegradable Polymers
  for Ophthalmology.....51
1$100
   MIV Therapeutics Inks Research Agreement with University of British Columbia.....52
Zimmer Acquires Implex.....52
Biomet Acquires Interpore.....52
Angiotech Acquires NeuColl.....52
1$100
   Synthes-Stratec Inc and Mathys Medizinaltechnik AG Merge.....53
Kyocera and Kobe Steel Form a Joint Venture.....53
Angiotech Expands Biomaterial Licensing Agreement with Poly-Med.....53
Genzyme Corp Enters into Agreement with Wyeth Pharmaceuticals.....53
1$100
   OctoPlus Grants License to SurModics to Acquire Two Novel Biodegradable
  Polymers.....54
GP Surgical Receives FDA Approval for TiMESH.....54
1$100
  12. FOCUS ON SELECT PLAYERS.....555 $395  
   A.P. Pharma, Inc. (USA).....55
Angiotech Pharmaceuticals Inc. (Canada).....55
Artimplant AB (Sweden).....55
1$100
   AST Products, Inc. (USA).....56
Biocoat, Inc. (USA).....56
DENTSPLY International Inc. (USA).....56
1$100
   Invibio (UK).....57
Integra LifeSciences Holdings Corporation (USA).....57
1$100
   Orthovita Inc. (USA).....58
SaluMedica, LLC (USA).....58
SurModics Inc. (USA).....58
1$100
   Synthes Inc. (USA).....59
United States Surgical (USA).....59
1$100
  13. GLOBAL MARKET PERSPECTIVE.....60   
   Table 2: World Recent Past, Current and Future Analysis for Biocompatible Materials by Geographic Region – North America, Japan, Europe, and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2007 through 2015 (includes corresponding Graph/Chart).....601$350
   Table 3: World Historic Review for Biocompatible Materials by Geographic Region –North America, Japan, Europe and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2006 (includes corresponding Graph/Chart).....611$350
   Table 4: World 11-Year Perspective for Biocompatible Materials by Geographic Region – Percentage Breakdown of Dollar Sales for North America, Japan, Europe, and Rest of World Markets for Years 2005, 2010 and 2015 (includes corresponding Graph/Chart).....621$350
   Table 5: World Recent Past, Current and Future Analysis for Polymeric Materials by Geographic Region – North America, Japan, Europe, and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2007 through 2015 (includes corresponding Graph/Chart).....631$350
   Table 6: World Historic Review for Polymeric Materials by Geographic Region –North America, Japan, Europe and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2006 (includes corresponding Graph/Chart).....641$350
   Table 7: World 11-Year Perspective for Polymeric Materials by Geographic Region – Percentage Breakdown of Dollar Sales for North America, Japan, Europe, and Rest of World Markets for Years 2005, 2010 and 2015 (includes corresponding Graph/Chart).....651$350
   Table 8: World Recent Past, Current and Future Analysis for Metallic Materials by Geographic Region – North America, Japan, Europe, and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2007 through 2015 (includes corresponding Graph/Chart).....661$350
   Table 9: World Historic Review for Metallic Materials by Geographic Region –North America, Japan, Europe and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2006 (includes corresponding Graph/Chart).....671$350
   Table 10: World 11-Year Perspective for Metallic Materials by Geographic Region – Percentage Breakdown of Dollar Sales for North America, Japan, Europe, and Rest of World Markets for Years 2005, 2010 and 2015 (includes corresponding Graph/Chart).....681$350
   Table 11: World Recent Past, Current and Future Analysis for Natural Materials by Geographic Region – North America, Japan, Europe, and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2007 through 2015 (includes corresponding Graph/Chart).....691$350
   Table 12: World Historic Review for Natural Materials by Geographic Region –North America, Japan, Europe and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2006 (includes corresponding Graph/Chart).....701$350
   Table 13: World 11-Year Perspective for Natural Materials by Geographic Region – Percentage Breakdown of Dollar Sales for North America, Japan, Europe, and Rest of World Markets for Years 2005, 2010 and 2015 (includes corresponding Graph/Chart).....711$350
   Table 14: World Recent Past, Current and Future Analysis for Other Materials by Geographic Region – North America, Japan, Europe, and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2007 through 2015 (includes corresponding Graph/Chart).....721$350
   Table 15: World Historic Review for Other Materials by Geographic Region –North America, Japan, Europe and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2006 (includes corresponding Graph/Chart).....731$350
   Table 16: World 11-Year Perspective for Other Materials by Geographic Region – Percentage Breakdown of Dollar Sales for North America, Japan, Europe, and Rest of World Markets for Years 2005, 2010 and 2015 (includes corresponding Graph/Chart).....741$350
  14. NORTH AMERICA.....756 $950  
   A. Market Analysis.....75
Outlook.....75
Demand for Orthopedic Biomaterials Surges.....75
1$100
   Orthopedic Biomaterials Emerge Recession Proof.....76
Developments in the United States Dental Biomaterial Market.....76
Regulatory Environment.....76
FDA Regulations.....76
1$100
   Potential Biomaterial Shortage.....77
Effects of Potential Shortages.....77
1$100
   B. Market Analytics.....78
Table 17: North America Recent Past, Current & Future Analysis for Biocompatible Materials by Type – Polymeric Materials, Metallic Materials, Natural Materials and Other Materials Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2007 through 2015 (includes corresponding Graph/Chart).....78
1$350
   Table 18: North America Historic Review for Biocompatible Materials by Type - Polymeric Materials, Metallic Materials, Natural Materials & Other Materials Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2006 (includes corresponding Graph/Chart).....791$350
   Table 19: North America 11-Year Perspective for Biocompatible Materials by Type – Percentage Breakdown of Dollar Sales for Polymeric Materials, Metallic Materials, Natural Materials and Other Materials Markets for 2005, 2010 and 2015 (includes corresponding Graph/Chart).....801$350
  15. JAPAN.....816 $1450  
   A. Market Analysis.....81
Outlook.....81
An Overview.....81
Import Scenario: Implants.....81
1$100
   Table 20: Japanese Percentage Imports by Implant Type (includes corresponding Graph/Chart).....82
History.....82
Major Biomaterial Research Groups.....82
Institute of Biomedical Engineering (Tokyo Women’s Medical University).....82
Tissue Engineering Research Institute (Kyoto University)......82
Institute of Biomaterials and Bioengineering (Tokyo Medical and Dental University).....82
1$350
   Principal Research Institutions.....83
Regulatory Environment.....83
Medical Affairs Law.....83
1$100
   B. Market Analytics.....84
Table 21: Japanese Recent Past, Current and Future Analysis for Biocompatible Materials by Type – Polymeric Materials, Metallic Materials, Natural Materials and Other Materials Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2007 through 2015 (includes corresponding Graph/Chart).....84
1$350
   Table 22: Japanese Historic Review for Biocompatible Materials by Type - Polymeric Materials, Metallic Materials, Natural Materials & Other Materials Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2006 (includes corresponding Graph/Chart).....851$350
   Table 23: Japanese 11-Year Perspective for Biocompatible Materials by Type – Percentage Breakdown of Dollar Sales for Polymeric Materials, Metallic Materials, Natural Materials and Other Materials Markets for 2005, 2010 and 2015 (includes corresponding Graph/Chart).....861$350
  16. EUROPE.....874 $950  
   A. Market Analysis.....87
Outlook.....87
Key Growth Factors.....87
UK Bioceramic Market.....87
Regulatory Environment.....87
Government Regulations.....87
1$100
   B. Market Analytics.....88
Table 24: European Recent Past, Current and Future Analysis for Biocompatible Materials by Type – Polymeric Materials, Metallic Materials, Natural Materials and Other Materials Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2007 through 2015 (includes corresponding Graph/Chart).....88
1$350
   Table 25: European Historic Review for Biocompatible Materials by Type - Polymeric Materials, Metallic Materials, Natural Materials & Other Materials Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2006 (includes corresponding Graph/Chart).....891$350
   Table 26: European 11-Year Perspective for Biocompatible Materials by Type – Percentage Breakdown of Dollar Sales for Polymeric Materials, Metallic Materials, Natural Materials and Other Materials Markets for Years 2005, 2010 and 2015 (includes corresponding Graph/Chart).....901$350
  17. REST OF WORLD.....913 $950  
   A. Market Analysis.....91
Outlook.....91
B. Market Analytics.....91
Table 27: Rest of World Recent Past, Current and Future Analysis for Biocompatible Materials by Type – Polymeric Materials, Metallic Materials, Natural Materials and Other Materials Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2007 through 2015 (includes corresponding Graph/Chart).....91
1$350
   Table 28: Rest of World Historic Review for Biocompatible Materials by Type - Polymeric Materials, Metallic Materials, Natural Materials & Other Materials Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2006 (includes corresponding Graph/Chart).....921$350
   Table 29: Rest of World 11-Year Perspective for Biocompatible Materials by Type – Percentage Breakdown of Dollar Sales for Polymeric Materials, Metallic Materials, Natural Materials and Other Materials Markets for 2005, 2010 and 2015 (includes corresponding Graph/Chart).....931$350
COMPETITION 263$995
  
Total Companies Profiled: 68 (including Divisions/Subsidiaries - 79)

Region/Country                 Players


The United States                 52    
Canada                             5
Japan                              2
Europe                            19 
     France                        1
     Germany                       3
     The United Kingdom            4
     Rest of Europe               11 
Middle-East                        1
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